Regenerative Potential of PDL-Derived Small Extracellular Vesicles
Language English Country United States Media print-electronic
Document type Journal Article
Grant support
Czech Science Foundation, project GACR 21-21409S
NIHR) Biomedical Research Centre based at Guy's and St Thomas' NHS Foundation Trust and King's College London
PubMed
39581762
PubMed Central
PMC12139699
DOI
10.1111/jre.13356
Knihovny.cz E-resources
- MeSH
- Cell Differentiation MeSH
- Extracellular Vesicles * physiology MeSH
- Fibroblasts physiology MeSH
- Gingiva cytology MeSH
- Wound Healing physiology MeSH
- Humans MeSH
- Osteogenesis physiology MeSH
- Periodontal Ligament * cytology physiology MeSH
- Regeneration * physiology MeSH
- Wnt Signaling Pathway physiology MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
Treatment of gingival fibroblasts with PDL extracellular vesicles results in promotion of Wnt signalling pathway and osteogenic differentiation. PDL secretome shows selective wound healing and matrix remodelling which can have implications for future periodontal regenerative strategies.
Centre of Excellence for Mass Spectrometry Denmark Hill King's College London London UK
Institute of Animal Physiology and Genetics Czech Academy of Sciences Brno Czech Republic
See more in PubMed
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