The Role of COVID-19 in Excess Mortality in Slovakia: A Novel Approach Based on Healthcare Billing Records
Language English Country Switzerland Media electronic-ecollection
Document type Journal Article
PubMed
39691547
PubMed Central
PMC11649408
DOI
10.3389/ijph.2024.1607537
PII: 1607537
Knihovny.cz E-resources
- Keywords
- COVID-19, COVID-19 associated death, COVID-19 confirmed death, Slovakia, excess mortality,
- MeSH
- COVID-19 * mortality MeSH
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Pandemics MeSH
- Cause of Death * MeSH
- Retrospective Studies MeSH
- SARS-CoV-2 MeSH
- Aged MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Geographicals
- Slovakia epidemiology MeSH
OBJECTIVES: Propose a methodology to identify COVID-19 associated deaths using healthcare billing records and evaluate its effectiveness by comparing the results with excess mortality data from 2020 to 2022 and confirmed COVID-19 deaths. METHODS: A retrospective quantitative analysis was conducted by merging healthcare billing records with cause of death data. The term "COVID-19 associated death" was defined as any death occurring within a defined timeframe following a confirmed contact with COVID-19. This category includes individuals who died directly due to COVID-19, with COVID-19 as a contributing factor, or as an aftermath of a COVID-19 infection, as well as those who died from other causes but had previously contracted COVID-19. This broader definition provides a more comprehensive measure of excess mortality compared to the officially confirmed COVID-19 deaths attributed to the virus. RESULTS: We identified 35,399 COVID-19 associated deaths during the 3-year pandemic in Slovakia compared to 21,395 confirmed COVID-19 deaths. CONCLUSION: The identification of COVID-19 associated deaths with our methodology offers a more accurate explanation for the notably high excess mortality observed in Slovakia (31,789 deaths) during the pandemic, relative to the EU27. Given the high level of excess mortality, the officially confirmed deaths are likely underestimated, and the presented methodology provides a more precise measure of mortality. Additionally, healthcare billing records prove valuable in identifying these deaths at the individual patient level using claims data of health insurance companies, which is crucial for implementing targeted preventive measures and improving preparedness for future pandemics.
Dôvera Health Insurance Company Bratislava Slovakia
Faculty of Management Prague University of Economics and Business Prague Czechia
Independent Healthcare Consultant Bratislava Slovakia
Institute for Healthcare Analyses Ministry of Health Bratislava Slovakia
Reporting and Health Statistics National Health Information Center Bratislava Slovakia
See more in PubMed
Mathieu E, Ritchie H, Rodés-Guirao L, Appel C, Giattino CH, Hasell J, et al. Coronavirus Pandemic COVID-19 (2023). Available from: https://ourworldindata.org/coronavirus (Accessed December 15, 2023).
COVID-19 Excess Mortality Collaborators. Estimating Excess Mortality Due to the COVID-19 Pandemic: A Systematic Analysis of COVID-19-Related Mortality, 2020–21. Lancet (2022) 399:1513–36. 10.1016/S0140-6736(21)02796-3 PubMed DOI PMC
Schumacher AE, Kyu HH, Aali A, Abbafati C, Abbas J, Abbasgholizadeh R, et al. Global Age-Sex-Specific Mortality, Life Expectancy, and Population Estimates in 204 Countries and Territories and 811 Subnational Locations, 1950–2021, and the Impact of the COVID-19 Pandemic: A Comprehensive Demographic Analysis for the Global Burden of Disease Study 2021. The Lancet (2024) 403(Issue 10440):1989–2056. 10.1016/s0140-6736(24)00476-8 PubMed DOI PMC
STATISTA. Slovakia: Death Rate From 2012 to 2022 (2022). Available from: https://www.statista.com/statistics/580944/death-rate-in-slovakia/ (Accessed March 20, 2024).
Eurostat. Excess Mortality – Statistics (2023). Available from: https://ec.europa.eu/eurostat/statistics-explained/index.php?title=Excess_mortality_-_statistics (Accessed August 23, 2023).
Sagan A, Bryndova L, Kowalska-Bobko I, Smatana M, Spranger A, Szerencses V, et al. A Reversal of Fortune: Comparison of Health System Responses to COVID-19 in the Visegrad Group during the Early Phases of the Pandemic. Health Policy (2022) 126:446–55. 10.1016/j.healthpol.2021.10.009 PubMed DOI PMC
Pujolar G, Oliver-Anglès A, Vargas I, Vázquez ML. Changes in Access to Health Services during the COVID-19 Pandemic: A Scoping Review. Int J Environ Res Public Health (2022) 19(3):1749. 10.3390/ijerph19031749 PubMed DOI PMC
World Health Organization. The True Death Toll of COVID-19 (2023). Available from: https://www.who.int/data/stories/the-true-death-toll-of-covid-19-estimating-global-excess-mortality (Accessed October 19, 2023).
Eurostat. Excess Mortality – Glossary (2023). Available from: https://ec.europa.eu/eurostat/statistics-explained/index.php?title=Glossary:Excess_mortality (Accessed November 21, 2023).
Goodman RA, Posner SF, Huang ES, Parekh AK, Koh HK. Defining and Measuring Chronic Conditions: Imperatives for Research, Policy, Program, and Practice. Prev Chronic Dis (2013) 10:E66. 10.5888/pcd10.120239 PubMed DOI PMC
R Core Team. R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing; (2021). Available from: https://www.R-project.org/ (Accessed October 17, 2024).
Národné centrum zdravotníckych informácií. Metodické Pokyny K Štandardom Zdravotníckej Informatiky (2023) Available from: https://www.nczisk.sk/Standardy-v-zdravotnictve/Pages/Metodicke-pokyny-k-standardom-zdravotnickej-informatiky.aspx (Accessed October 19, 2023).
Section 15 (6) of Act No. 581/2004 Coll. On Health Insurance Companies, Health Care Supervision and on the Amendment and Supplementing of Certain Laws, as Amended and Pursuant to Act No. 153/2013 Coll. on the National Health Information System and on the Amendment and Supplementing of Certain Laws, as Amended (2024).
Úrad pre dohľad nad zdravotnou starostlivosťou. List O Prehliadke Mŕtveho a Štatistické Hlásenie O Smrti (2023). Available from: https://www.udzs-sk.sk/documents/14214/17028/list_o_prehliadke_mrtveho_a_statisticke_hlasenie_o_umrti_2018.PDF (Accessed November 22, 2023).
DRG. MKCH Číselník (2023). Available from: https://www.drg.sk/(Accessed December 15, 2023).
NCZI. MEDZINÁRODNÁ KLASIFIKÁCIA CHORÔB - MKCH-10 (2024). Available from: https://www.nczisk.sk/Standardy-v-zdravotnictve/Pages/Medzinarodna-klasifikacia-chorob-MKCH-10.aspx (Accessed September 5, 2024).
DRG. COVID-19 (2024). Available from: https://www.drg.sk/pk/S0103f/covid-19/(Accessed March 8, 2024).
Hernández-Aceituno A, García-Hernández A, Larumbe-Zabala E. COVID-19 Long-Term Sequelae: Omicron versus Alpha and Delta Variants. Infect Dis Now (2023) 53(Issue 5):104688. 10.1016/j.idnow.2023.104688 PubMed DOI PMC
Wang C, Liu B, Zhang S, Huang N, Zhao T, Lu QB, et al. Differences in Incidence and Fatality of COVID-19 by SARS-CoV-2 Omicron Variant versus Delta Variant in Relation to Vaccine Coverage: A World-wide Revie. J Med Virol (2022) 95(1):e28118. 10.1002/jmv.28118 PubMed DOI PMC
Adu P, Popoola T, Medvedev ON, Collings S, Mbinta J, Aspin C, et al. Implications for COVID-19 Vaccine Uptake: A Systematic Review. J Infect Public Health (2023) 16(3):441–66. 10.1016/j.jiph.2023.01.020 PubMed DOI PMC
Siddiqui S, Saeed AHW, Ahmed AH. Recent Chronology of COVID-19 Pandemic. Front Public Health (2022) 10:778037. 10.3389/fpubh.2022.778037 PubMed DOI PMC
Dobrowolska K, Brzdęk M, Zarębska-Michaluk D, Rzymski P, Rogalska M, Moniuszko-Malinowska A, et al. Differences between the Course of SARS-CoV-2 Infections in the Periods of the Delta and Omicron Variant Dominance in Poland. Pol Arch Intern Med (2023) 133:16403. 10.20452/pamw.16403 PubMed DOI
OECD. State of Health in the EU: Slovensko, Zdravotný Profil Krajiny. WHO; (2021). Available from: https://health.ec.europa.eu/system/files/2022-01/2021_chp_sk_slovak.pdf (Accessed September 7, 2024).
Harrison SL, Buckley BJR, Rivera-Caravaca JM, Zhang J, Lip GYH. Cardiovascular Risk Factors, Cardiovascular Disease, and COVID-19: An Umbrella Review of Systematic Reviews. Eur Heart J Qual Care Clin Outcomes (2021) 7:330–9. 10.1093/ehjqcco/qcab029 PubMed DOI PMC
Lacka J, Mrázová M, Ištokovičová P, Mužik R, Martinka E. Úmrtnosť Pacientov S Diabetes Mellitus Na Slovensku Počas Pandémie COVID-19. Lekárske noviny (2021) 11:12.
Gupta S, Hayek SS, Wang W, Chan L, Mathews KS, Melamed ML, et al. Factors Associated with Death in Critically Ill Patients with Coronavirus Disease 2019 in the US. JAMA Intern Med (2020) 180(11):1436–47. 10.1001/jamainternmed.2020.3596 PubMed DOI PMC
Bedston S, Almaghrabi F, Patterson L, Agrawal U, Woolford L, Anand SN, et al. Risk of Severe COVID-19 Outcomes After Autumn 2022 COVID-19 Booster Vaccinations: A Pooled Analysis of National Prospective Cohort Studies Involving 7.4 Million Adults in England, Northern Ireland, Scotland and Wales. Lancet Reg Health Eur (2024) 37:100816. 10.1016/j.lanepe.2023.100816 PubMed DOI PMC
Iuliano AD, Chang HH, Patel NN, Threlkel R, Kniss K, Reich J, et al. Estimating Under-Recognized COVID-19 Deaths, United States, March 2020-May 2021 Using an Excess Mortality Modelling Approach. Lancet Reg. Health Am. (2021) 1:100019. 10.1016/j.lana.2021.100019 PubMed DOI PMC
Sudat SEK, Robinson SC, Mudiganti S, Mani A, Pressman AR. Mind the Clinical-Analytic Gap: Electronic Health Records and COVID-19 Pandemic Response. J Biomed Inform (2021) 116:103715. 10.1016/j.jbi.2021.103715 PubMed DOI PMC
Pažitný P, Kandilaki D, Mužik R, Benková B. COVID-19 Case Fatality Rate in the Context of Healthcare System Organization and EHCI Performance: Focus on the Visegrad (V4) Countries. Acta Oeconomica (2021) 71(S1):35–52. 10.1556/032.2021.00028 DOI
Cho SI, Yoon S, Lee HJ. Impact of Comorbidity Burden on Mortality in Patients with COVID-19 Using the Korean Health Insurance Database. Scientific Rep (2021) 11(1):6375. 10.1038/s41598-021-85813-2 PubMed DOI PMC
Byeon KH, Kim DW, Kim J, Choi BY, Choi B, Cho KD. Factors Affecting the Survival of Early COVID-19 Patients in South Korea: An Observational Study Based on the Korean National Health Insurance Big Data. Int J Infect Dis (2021) 105:588–94. 10.1016/j.ijid.2021.02.101 PubMed DOI PMC
Woolf SH, Chapman DA, Sabo RT, Zimmerman EB. Excess Deaths from COVID-19 and Other Causes in the US, March 1, 2020, to January 2, 2021. Jama (2021) 325(17):1786–9. 10.1001/jama.2021.5199 PubMed DOI PMC
Weinberger DM, Chen J, Cohen T, Crawford FW, Mostashari F, Olson D, et al. Estimation of Excess Deaths Associated with the COVID-19 Pandemic in the United States, March to May 2020. JAMA Intern Med (2020) 180(10):1336–44. 10.1001/jamainternmed.2020.3391 PubMed DOI PMC
Ciminelli G, Garcia-Mandicó S. COVID-19 in Italy: An Analysis of Death Registry Data. J Public Health (2020) 42(4):723–30. 10.1093/pubmed/fdaa165 PubMed DOI PMC