Metastases of the articular process, temporomandibular joint (TMJ), are rare findings. Their frequency is around 5% of patients with metastatic involvement of the mandible. The most common primary tumor is adenocarcinoma of the lung in women and adenocarcinoma of the prostate in men. The authors present 3 patients with TMJ metastasis. These were metastasis of breast adenocarcinoma, prostate adenocarcinoma, and lung adenocarcinoma. TMJ metastases are rare but complicated to diagnose because their presence may be accompanied by symptoms typical of other TMJ diseases (discopathy, arthritis, osteoarthritis). However, the authors recommend the unequivocal exclusion of a metastatic process in cases where the patient has a positive cancer history and their complaints do not respond to usual therapy.

Department of Oral and Maxillofacial Surgery Oral Maxillofacial Surgery Charles University and Faculty Hospital Prague Prague

Department of Oral and Maxillofacial Surgery University Hospital Olomouc and Palacky University Olomouc Olomouc Czech Republic

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Gangwani P, Sadda A, Danakas A, et al. Metastatic disease to the condyle: a case report and review of literature. Oral Maxillofac Surg Cases 2022;8:e100244

Olivera C, Mouallemb G, Dutot-Philipeau N, et al. A case report of condyle metastasis and a review of the literature. J Stomatol Oral Maxillofac Surg 2022;123:360–363

Labradora AJP, Marinb NRG, Valdezc LHM, et al. Metastasis to the oral and maxillofacial region. A systematic review. J Stomatol Oral Maxillofac Surg 2022;123:e474–e483

Freudlsperger C, Kurth R, Werner MK, et al. Condylar metastasis from prostatic carcinoma mimicking temporomandibular disorder: a case report. Oral Maxillofac Surg 2012;16:79–82

Chang VKO, Thambar S. TMJ pain as a presentation of metastatic breast cancer to the right mandibular condyle. BMJ Case Rep 2021;14:e241601

Matsuda S, Yoshimura H, Kondo S, et al. Temporomandibular dislocation caused by pancreatic cancer metastasis: a case report. Oncol Lett 2017;14:6053–6058

Vairac LA, Massarelli O, Deiana A, et al. The mandibular condyle as uncommon metastatic site of neuroendocrine carcinoma: case report and review of literature. J Oral Maxillofac Surg Med Pathol 2017;29:314–320

Menezes JD, Cappellari PF, Capelari MM. Mandibular metastasis of adenocarcinoma from prostate cancer: case report according to epidemiology and current therapeutical trends of the advanced prostate cancer. J Appl Oral Sci 2013;21:490–495

Scolozzi P, Becker M, Lombardi T. Mandibular condylar metastasis mimicking acute internal derangement of the temporomandibular joint. J Can Dent Assoc 2012;78:c77

Dodo M, Kumagai M, Kato Y, et al. Metastasis in the mandibular condyle: a case report.. J Med Case Rep 2017;11:323