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Understanding buffering of metabolic acidosis in critically ill: keep an open mind

. 2025 Mar ; 51 (3) : 650-651. [epub] 20250217

Status In-Process Language English Country United States Media print-electronic

Document type Letter

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PubMed 39961839
DOI 10.1007/s00134-025-07811-6
PII: 10.1007/s00134-025-07811-6
Knihovny.cz E-resources

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Giosa L, Camporota L, Langer T (2024) Understanding buffering of metabolic acidosis in critical illness. Intensive Care Med 50(11):1925–1928. https://doi.org/10.1007/s00134-024-07656-5 . (Epub 2024 Sep 23) PubMed DOI

Van Slyke DD (1922) On the measurement of buffer values and on the relationship of buffer value to the dissociation constant of the buffer and the concentration and reaction of the buffer solution. J Biol Chem 52:525–570. https://doi.org/10.1016/S0021-9258(18)85845-8 DOI

Krbec M, Waldauf P, Zadek F, Brusatori S, Zanella A, Duška F, Langer T (2022) Non-carbonic buffer power of whole blood is increased in experimental metabolic acidosis: an in-vitro study. Front Physiol 21(13):1009378. https://doi.org/10.3389/fphys.2022.1009378 DOI

Krbec M, Duška F, Elbers PWG (2023) Toward a unified understanding of blood buffer power. J Appl Physiol (1985) 135(1):202. https://doi.org/10.1152/japplphysiol.00320.2023 PubMed DOI

Heldeweg MLA, Berend K, Schober P, Duška F (2024) Understanding the acid-base response to respiratory derangements: finding, and clinically applying, the in vivo base excess. Crit Care Explor 6(12):e1191. https://doi.org/10.1097/CCE.0000000000001191 PubMed DOI PMC

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