NLR Proteins [NLR proteiny]

topical
4
Terms

NLR rodina proteinů
NOD-like receptory
proteiny rodiny NLR

 

NLR Protein
NOD-like Receptor
NOD-like Receptors
Nucleotide-Binding Domain Leucine-Rich Repeat Protein
Nucleotide-binding Domain Leucine-rich Repeat Proteins

Definition

Intracellular signaling proteins that are defined by the presence of a NUCLEOTIDE-binding region and LEUCINE-rich repeats. Their general structure consists of any of a variety of effector domains at their N-termini such as a caspase recruitment domain (CARD), a central nucleotide-binding domain, and a variable number of C-terminal leucine-rich repeats. They are important for pathogen recognition in the INNATE IMMUNE RESPONSE of animals and plants. Members of the NLR protein family include the NOD SIGNALING ADAPTOR PROTEINS.

DUI
D000070576 MeSH Browser
CUI
M000610980
Previous indexing
Nod Signaling Adaptor Proteins (2007-2016)
History note
2017
Public note
2017

D Chemicals and Drugs
D10 Lipids 2 524
D12.644 Peptides 1 380
D12.644.360.087 Calcineurin 76
D12.644.360.262 Cyclins 112
D12.644.360.365 I-kappa B Proteins 5
D12.644.360.410 Mesothelin 2
D12.644.360.534 Mucin-4 5
D12.644.360.539 NLR Proteins 4
D12.644.360.539.500 Nod Signaling Adaptor Proteins 1
D12.644.360.650 RNA-Binding Protein EWS 15