Intracellular signaling proteins that are defined by the presence of a NUCLEOTIDE-binding region and LEUCINE-rich repeats. Their general structure consists of any of a variety of effector domains at their N-termini such as a caspase recruitment domain (CARD), a central nucleotide-binding domain, and a variable number of C-terminal leucine-rich repeats. They are important for pathogen recognition in the INNATE IMMUNE RESPONSE of animals and plants. Members of the NLR protein family include the NOD SIGNALING ADAPTOR PROTEINS.

DUI

D000070576 MeSH Prohlížeč

CUI

M000610980

Předchozí užití

Nod Signaling Adaptor Proteins (2007-2016)

Historická pozn.

2017

Veřejná pozn.

2017