Perilipin-2 [perilipin 2] topical
- Terms
-
adipofilin
PLIN2
-
Adipophilin
Adipose Differentiation-Related Protein
ADRP Protein
Perilipin 2 Protein
PLIN2 Protein
A perilipin that is expressed by many different cell types. It binds FATTY ACIDS and CHOLESTEROL, stabilizes TRIGLYCERIDES, and localizes to both the surface and hydrophobic core of LIPID DROPLETS, as well as the ENDOPLASMIC RECTICULUM and PLASMA MEMBRANE in MACROPHAGES. It also plays a central role in the biogenesis of lipid droplets and FOAM CELLS and is highly expressed by macrophages at atherosclerotic lesions in human arteries along with the INFLAMMATION markers TNF-ALPHA; MCP-1 RECEPTOR; and IL-6.
- DUI
- D000070780
- CUI
- M0298231
- History note
- 2017 (1998)
- Public note
- 2017; PERILIPIN-2 was indexed under PEPTIDES 1998-2011; and under MEMBRANE PROTEINS 2011-2016
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AG
- agonists 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 0
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 0
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 1
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
D02 Organic Chemicals
D03 Heterocyclic Compounds
D04 Polycyclic Compounds
D05 Macromolecular Substances
D06 Hormones, Hormone Substitutes, and Hormone Antagonists
D08 Enzymes and Coenzymes
D09 Carbohydrates
D10 Lipids
D12 Amino Acids, Peptides, and Proteins
D12.776 Proteins
D12.776.157 Carrier Proteins
D12.776.157.464 Lipid Droplet Associated Proteins
D12.776.157.464.500 Perilipins
D12.776.157.464.500.500 Perilipin-1
D12.776.157.464.500.750 Perilipin-2
D12.776.157.464.500.875 Perilipin-3
D12.776.157.464.500.906 Perilipin-4
D12.776.157.464.500.937 Perilipin-5
D13 Nucleic Acids, Nucleotides, and Nucleosides
D20 Complex Mixtures
D23 Biological Factors
D25 Biomedical and Dental Materials
D26 Pharmaceutical Preparations
D27 Chemical Actions and Uses