perilipin 2 [Perilipin-2] tematický

Termíny

adipofilin
PLIN2

 

Adipophilin
Adipose Differentiation-Related Protein
ADRP Protein
Perilipin 2 Protein
PLIN2 Protein

Perzistentní odkaz   https://www.medvik.cz/link/D000070780
Definice

A perilipin that is expressed by many different cell types. It binds FATTY ACIDS and CHOLESTEROL, stabilizes TRIGLYCERIDES, and localizes to both the surface and hydrophobic core of LIPID DROPLETS, as well as the ENDOPLASMIC RECTICULUM and PLASMA MEMBRANE in MACROPHAGES. It also plays a central role in the biogenesis of lipid droplets and FOAM CELLS and is highly expressed by macrophages at atherosclerotic lesions in human arteries along with the INFLAMMATION markers TNF-ALPHA; MCP-1 RECEPTOR; and IL-6.

DUI
D000070780
CUI
M0298231
Historická pozn.
2017 (1998)
Veřejná pozn.
2017; PERILIPIN-2 was indexed under PEPTIDES 1998-2011; and under MEMBRANE PROTEINS 2011-2016