Beclin-1 [beclin 1]
- Terms
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beclin-1
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ATG-6 Protein
ATG6 Protein
Beclin-1 Protein
Beclin1
Coiled-coil Myosin-like Bcl2-interacting Protein
GT197 Protein
An autophagy related protein which functions as a core subunit of PHOSPHATIDYLINOSITOL 3-KINASE MULTIPROTEIN COMPLEXES. It mediates the formation of phosphatidylinositol 3-phosphate and functions in AUTOPHAGY, where it is required for maturation of the AUTOPHAGOSOME. It also functions in ENDOCYTOSIS and CYTOKINESIS as part of a separate complex. Beclin-1 associates with INTRACELLULAR MEMBRANES and interacts with the PROTO-ONCOGENE PROTEINS C-BCL-2 and BCL-X PROTEIN.
- DUI
- D000071186 MeSH Browser
- CUI
- M000613469
- Previous indexing
- Apoptosis Regulatory Proteins (2006-2016); Membrane Proteins (2006-2016)
- History note
- 2017
- Public note
- 2017
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