Beclin-1 [beclin 1]

topical
3
Terms

beclin-1

 

ATG-6 Protein
ATG6 Protein
Beclin-1 Protein
Beclin1
Coiled-coil Myosin-like Bcl2-interacting Protein
GT197 Protein

Definition

An autophagy related protein which functions as a core subunit of PHOSPHATIDYLINOSITOL 3-KINASE MULTIPROTEIN COMPLEXES. It mediates the formation of phosphatidylinositol 3-phosphate and functions in AUTOPHAGY, where it is required for maturation of the AUTOPHAGOSOME. It also functions in ENDOCYTOSIS and CYTOKINESIS as part of a separate complex. Beclin-1 associates with INTRACELLULAR MEMBRANES and interacts with the PROTO-ONCOGENE PROTEINS C-BCL-2 and BCL-X PROTEIN.

DUI
D000071186 MeSH Browser
CUI
M000613469
Previous indexing
Apoptosis Regulatory Proteins (2006-2016); Membrane Proteins (2006-2016)
History note
2017
Public note
2017

D Chemicals and Drugs
D12.644 Peptides 1 380
D12.644.360.075.311 Apoptosis Inducing Factor 10
D12.644.360.075.323 Bcl-2-Like Protein 11 5
D12.644.360.075.335 Beclin-1 3
D12.644.360.075.358 CARD Signaling Adaptor Proteins 7
D12.644.360.075.413 DCC Receptor
D12.644.360.075.437 Inhibitor of Apoptosis Proteins 29
D12.644.360.075.718 Proto-Oncogene Proteins c-bcl-2 147
D12.776 Proteins 2 575
D12.776.094.500 Beclin-1 3
D12.776.094.750 Sequestosome-1 Protein 3
D12.776.476.075.311 Apoptosis Inducing Factor 10
D12.776.476.075.323 Bcl-2-Like Protein 11 5
D12.776.476.075.335 Beclin-1 3
D12.776.476.075.358 CARD Signaling Adaptor Proteins 7
D12.776.476.075.405 Caspases 157
D12.776.476.075.413 DCC Receptor
D12.776.476.075.437 Inhibitor of Apoptosis Proteins 29
D12.776.476.075.718 Proto-Oncogene Proteins c-bcl-2 147