Synthetic Lethal Mutations [umělé letální mutace]

topical
4
Terms

indukovaná letální mutace
syntetická letalita

 

Synthetic Lethal Mutation
Synthetic Lethality

Persistent link   https://www.medvik.cz/link/D000072020
Definition

Mutations in genes which lead to cell or organism death when occurring in combination with mutations in one or more other genes.

DUI
D000072020 MeSH Browser
CUI
M000616244
History note
2017
Public note
2017

Allowable subheadings

DE
drug effects 0
GE
genetics 0
IM
immunology 0
PH
physiology 0
RE
radiation effects 0

G Phenomena and Processes
G01 Physical Phenomena 77
G02 Chemical Phenomena 307
G03 Metabolic Phenomena obsolete
G04 Cell Physiological Phenomena 514
G05 Genetic Phenomena 135
G05.365 Genetic Variation 858
G05.365.590 Mutation 4 993
G05.365.590.029 Allelic Imbalance 2
G05.365.590.060 Base Pair Mismatch 14
G05.365.590.175 Chromosome Aberrations 1 574
G05.365.590.195 Codon, Nonsense 52
G05.365.590.220 DNA Repeat Expansion 7
G05.365.590.265 Frameshift Mutation 47
G05.365.590.288 Gain of Function Mutation 18
G05.365.590.310 Gene Amplification 333
G05.365.590.320 Gene Duplication 65
G05.365.590.335 Genomic Instability 87
G05.365.590.350 Germ-Line Mutation 199
G05.365.590.500 INDEL Mutation 17
G05.365.590.538 Loss of Function Mutation 12
G05.365.590.575 Mutagenesis, Insertional 56
G05.365.590.594 Mutation Accumulation 3
G05.365.590.612 Mutation Rate 18
G05.365.590.650 Mutation, Missense 212
G05.365.590.675 Point Mutation 246
G05.365.590.762 Sequence Deletion 104
G05.365.590.770 Sequence Inversion 2
G05.365.590.803 Silent Mutation 2
G05.365.590.835 Suppression, Genetic 29
G05.365.590.917 Synthetic Lethal Mutations 4
G06 Microbiological Phenomena 96
G07 Physiological Phenomena 176
G08 Reproductive and Urinary Physiological Phenomena 18
G09 Circulatory and Respiratory Physiological Phenomena 94
G10 Digestive System and Oral Physiological Phenomena 4
G11 Musculoskeletal and Neural Physiological Phenomena 16
G12 Immune System Phenomena 248
G13 Integumentary System Physiological Phenomena 14
G14 Ocular Physiological Phenomena 147
G15 Plant Physiological Phenomena 158
G16 Biological Phenomena 129
G17 Mathematical Concepts 66

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