Genomic Instability [nestabilita genomu]

topical
88
Terms

genom - nestabilita
genomová nestabilita
genomová stabilita
stabilita genomu

 

Genome Instability
Genome Stability
Genomic Stability

Persistent link   https://www.medvik.cz/link/D042822
Definition

An increased tendency of the GENOME to acquire MUTATIONS when various processes involved in maintaining and replicating the genome are dysfunctional.

DUI
D042822 MeSH Browser
CUI
M0442085
History note
2004
Public note
2004

Allowable subheadings

DE
drug effects 5
ES
ethics
GE
genetics 14
IM
immunology 1
PH
physiology 5
RE
radiation effects 7

C Diseases
C23 Pathological Conditions, Signs and Symptoms 451
C23.550 Pathologic Processes 195
C23.550.035 Acantholysis 10
C23.550.073 Arrhythmias, Cardiac 2 797
C23.550.081 Ascites 335
C23.550.113 Atrial Remodeling 13
C23.550.145 Azotemia 5
C23.550.161 Cardiotoxicity 142
C23.550.177 Channelopathies 14
C23.550.210 Chromosome Aberrations 1 578
C23.550.260 Death 1 400
C23.550.274 Dehydration 403
C23.550.277 Delayed Graft Function 25
C23.550.288 Disease 1 712
C23.550.291 Disease Attributes 1 208
C23.550.308 Dysbiosis 107
C23.550.325 Emphysema 89
C23.550.340 Extravasation of Diagnostic and Therapeutic Materials 36
C23.550.347 Femoracetabular Impingement 27
C23.550.355 Fibrosis 366
C23.550.359 Frailty 122
C23.550.362 Genomic Instability 88
C23.550.362.180 Chromosomal Instability 40
C23.550.362.590 Microsatellite Instability 67
C23.550.369 Gliosis 37
C23.550.382 Granuloma 236
C23.550.384 Granulomatosis, Orofacial 6
C23.550.393 Growth Disorders 636
C23.550.403 Hemolysis 384
C23.550.414 Hemorrhage 2 296
C23.550.421 Hyperammonemia 31
C23.550.425 Hyperamylasemia 5
C23.550.429 Hyperbilirubinemia 184
C23.550.444 Hyperplasia 340
C23.550.449 Hyperuricemia 225
C23.550.455 Hypovolemia 87
C23.550.470 Inflammation 3 480
C23.550.505 Intraoperative Complications 717
C23.550.513 Ischemia 1 731
C23.550.522 Leukoaraiosis 4
C23.550.526 Leukocytosis 98
C23.550.537 Lithiasis 87
C23.550.543 Long Term Adverse Effects 7
C23.550.548 Malacoplakia 4
C23.550.568 Menstruation Disturbances 353
C23.550.589 Metaplasia 98
C23.550.695 Muscle Weakness 225
C23.550.706 Myotoxicity 1
C23.550.717 Necrosis 837
C23.550.722 Neointima 8
C23.550.727 Neoplastic Processes 130
C23.550.737 Nerve Degeneration 166
C23.550.744 Ochronosis 42
C23.550.751 Ossification, Heterotopic 139
C23.550.753 Ototoxicity 10
C23.550.755 Pigmentation Disorders 132
C23.550.759 Polydipsia 17
C23.550.767 Postoperative Complications 7 077
C23.550.770 Protein Aggregation, Pathological 16
C23.550.773 Respiratory Aspiration 79
C23.550.794 Retropneumoperitoneum 14
C23.550.823 Sclerosis 84
C23.550.835 Shock 410
C23.550.863 Teratogenesis 27
C23.550.877 Toxic Optic Neuropathy 1
C23.550.891 Ulcer 201
C23.550.918 Vascular Remodeling 29
C23.550.945 Yang Deficiency 9
C23.550.972 Yin Deficiency 9

G Phenomena and Processes
G05 Genetic Phenomena 135
G05.045 Biological Evolution 1 260
G05.090 Breeding 146
G05.113 Cell Division 848
G05.135 Cellular Reprogramming 57
G05.158 Clonal Evolution 28
G05.180 Consanguinity 82
G05.193 DNA Cleavage 15
G05.200 DNA Damage 966
G05.206 DNA Methylation 444
G05.213 DNA Packaging 3
G05.219 DNA Repair 472
G05.226 DNA Replication 289
G05.232 DNA Transformation Competence
G05.285 Founder Effect 20
G05.297 Gene Expression 1 552
G05.308 Gene Expression Regulation 1 080
G05.330 Gene Frequency 442
G05.340 Gene Order 43
G05.342 Gene Pool 6
G05.344 Gene Rearrangement 184
G05.346 Genetic Background 14
G05.347 Genetic Fitness 29
G05.348 Genetic Linkage 93
G05.350 Genetic Load 21
G05.355 Genetic Processes obsolete
G05.360 Genetic Structures 25
G05.365 Genetic Variation 861
G05.365.590 Mutation 5 036
G05.365.590.029 Allelic Imbalance 2
G05.365.590.060 Base Pair Mismatch 14
G05.365.590.175 Chromosome Aberrations 1 578
G05.365.590.195 Codon, Nonsense 52
G05.365.590.220 DNA Repeat Expansion 7
G05.365.590.265 Frameshift Mutation 47
G05.365.590.288 Gain of Function Mutation 18
G05.365.590.310 Gene Amplification 334
G05.365.590.320 Gene Duplication 65
G05.365.590.335 Genomic Instability 88
G05.365.590.335.590 Microsatellite Instability 67
G05.365.590.350 Germ-Line Mutation 202
G05.365.590.500 INDEL Mutation 17
G05.365.590.538 Loss of Function Mutation 13
G05.365.590.575 Mutagenesis, Insertional 56
G05.365.590.594 Mutation Accumulation 3
G05.365.590.612 Mutation Rate 18
G05.365.590.650 Mutation, Missense 216
G05.365.590.675 Point Mutation 246
G05.365.590.762 Sequence Deletion 104
G05.365.590.770 Sequence Inversion 2
G05.365.590.803 Silent Mutation 2
G05.365.590.835 Suppression, Genetic 29
G05.365.590.917 Synthetic Lethal Mutations 4
G05.370 Genomic Instability 88
G05.370.180 Chromosomal Instability 40
G05.370.590 Microsatellite Instability 67
G05.380 Genotype 1 918
G05.390 Heredity 210
G05.400 Hybrid Vigor 7
G05.410 Inbreeding Depression
G05.420 Inheritance Patterns 50
G05.545 Molecular Mimicry 38
G05.558 Mutagenesis 276
G05.627 Nucleic Acid Denaturation 62
G05.695 Phenotype 2 246
G05.700 Ploidies 90
G05.728 Recombination, Genetic 262
G05.755 RNA Cleavage 6
G05.762 RNA Damage
G05.769 RNA Replication
G05.783 Selection, Genetic 143
G05.810 Sequence Homology 74
G05.813 Sex Determination Processes 58
G05.815 Sex Ratio 96
G05.820 Structural Homology, Protein 30
G05.910 Sympatry 25
G05.935 Virus Integration 32

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