Genomic Instability [nestabilita genomu]

topical
87
Terms

genom - nestabilita
genomová nestabilita
genomová stabilita
stabilita genomu

 

Genome Instability
Genome Stability
Genomic Stability

Persistent link   https://www.medvik.cz/link/D042822
Definition

An increased tendency of the GENOME to acquire MUTATIONS when various processes involved in maintaining and replicating the genome are dysfunctional.

DUI
D042822 MeSH Browser
CUI
M0442085
History note
2004
Public note
2004

Allowable subheadings

DE
drug effects 5
ES
ethics 0
GE
genetics 12
IM
immunology 1
PH
physiology 5
RE
radiation effects 7

C Diseases
C23 Pathological Conditions, Signs and Symptoms 451
C23.550 Pathologic Processes 195
C23.550.035 Acantholysis 10
C23.550.073 Arrhythmias, Cardiac 2 786
C23.550.081 Ascites 333
C23.550.113 Atrial Remodeling 13
C23.550.145 Azotemia 5
C23.550.161 Cardiotoxicity 138
C23.550.177 Channelopathies 13
C23.550.210 Chromosome Aberrations 1 574
C23.550.260 Death 1 392
C23.550.274 Dehydration 401
C23.550.277 Delayed Graft Function 24
C23.550.288 Disease 1 706
C23.550.291 Disease Attributes 1 207
C23.550.308 Dysbiosis 103
C23.550.325 Emphysema 89
C23.550.340 Extravasation of Diagnostic and Therapeutic Materials 36
C23.550.347 Femoracetabular Impingement 27
C23.550.355 Fibrosis 362
C23.550.359 Frailty 115
C23.550.362 Genomic Instability 87
C23.550.362.180 Chromosomal Instability 39
C23.550.362.590 Microsatellite Instability 63
C23.550.369 Gliosis 37
C23.550.382 Granuloma 236
C23.550.384 Granulomatosis, Orofacial 6
C23.550.393 Growth Disorders 633
C23.550.403 Hemolysis 382
C23.550.414 Hemorrhage 2 283
C23.550.421 Hyperammonemia 31
C23.550.425 Hyperamylasemia 5
C23.550.429 Hyperbilirubinemia 184
C23.550.444 Hyperplasia 337
C23.550.449 Hyperuricemia 218
C23.550.455 Hypovolemia 87
C23.550.470 Inflammation 3 448
C23.550.505 Intraoperative Complications 714
C23.550.513 Ischemia 1 730
C23.550.522 Leukoaraiosis 4
C23.550.526 Leukocytosis 97
C23.550.537 Lithiasis 87
C23.550.543 Long Term Adverse Effects 7
C23.550.548 Malacoplakia 4
C23.550.568 Menstruation Disturbances 353
C23.550.589 Metaplasia 97
C23.550.695 Muscle Weakness 224
C23.550.706 Myotoxicity 1
C23.550.717 Necrosis 832
C23.550.722 Neointima 8
C23.550.727 Neoplastic Processes 130
C23.550.737 Nerve Degeneration 166
C23.550.744 Ochronosis 42
C23.550.751 Ossification, Heterotopic 139
C23.550.753 Ototoxicity 10
C23.550.755 Pigmentation Disorders 132
C23.550.759 Polydipsia 17
C23.550.767 Postoperative Complications 7 048
C23.550.770 Protein Aggregation, Pathological 15
C23.550.773 Respiratory Aspiration 78
C23.550.794 Retropneumoperitoneum 14
C23.550.823 Sclerosis 84
C23.550.835 Shock 409
C23.550.863 Teratogenesis 27
C23.550.877 Toxic Optic Neuropathy 1
C23.550.891 Ulcer 201
C23.550.918 Vascular Remodeling 29
C23.550.945 Yang Deficiency 8
C23.550.972 Yin Deficiency 8

G Phenomena and Processes
G05 Genetic Phenomena 135
G05.045 Biological Evolution 1 257
G05.090 Breeding 146
G05.113 Cell Division 848
G05.135 Cellular Reprogramming 56
G05.158 Clonal Evolution 28
G05.180 Consanguinity 79
G05.193 DNA Cleavage 15
G05.200 DNA Damage 956
G05.206 DNA Methylation 437
G05.213 DNA Packaging 3
G05.219 DNA Repair 465
G05.226 DNA Replication 287
G05.232 DNA Transformation Competence
G05.285 Founder Effect 20
G05.297 Gene Expression 1 547
G05.308 Gene Expression Regulation 1 073
G05.330 Gene Frequency 440
G05.340 Gene Order 43
G05.342 Gene Pool 6
G05.344 Gene Rearrangement 180
G05.346 Genetic Background 11
G05.347 Genetic Fitness 29
G05.348 Genetic Linkage 93
G05.350 Genetic Load 21
G05.355 Genetic Processes obsolete
G05.360 Genetic Structures 25
G05.365 Genetic Variation 858
G05.365.590 Mutation 4 993
G05.365.590.029 Allelic Imbalance 2
G05.365.590.060 Base Pair Mismatch 14
G05.365.590.175 Chromosome Aberrations 1 574
G05.365.590.195 Codon, Nonsense 52
G05.365.590.220 DNA Repeat Expansion 7
G05.365.590.265 Frameshift Mutation 47
G05.365.590.288 Gain of Function Mutation 18
G05.365.590.310 Gene Amplification 333
G05.365.590.320 Gene Duplication 65
G05.365.590.335 Genomic Instability 87
G05.365.590.335.590 Microsatellite Instability 63
G05.365.590.350 Germ-Line Mutation 199
G05.365.590.500 INDEL Mutation 17
G05.365.590.538 Loss of Function Mutation 12
G05.365.590.575 Mutagenesis, Insertional 56
G05.365.590.594 Mutation Accumulation 3
G05.365.590.612 Mutation Rate 18
G05.365.590.650 Mutation, Missense 212
G05.365.590.675 Point Mutation 246
G05.365.590.762 Sequence Deletion 104
G05.365.590.770 Sequence Inversion 2
G05.365.590.803 Silent Mutation 2
G05.365.590.835 Suppression, Genetic 29
G05.365.590.917 Synthetic Lethal Mutations 4
G05.370 Genomic Instability 87
G05.370.180 Chromosomal Instability 39
G05.370.590 Microsatellite Instability 63
G05.380 Genotype 1 906
G05.390 Heredity 210
G05.400 Hybrid Vigor 7
G05.410 Inbreeding Depression
G05.420 Inheritance Patterns 50
G05.545 Molecular Mimicry 37
G05.558 Mutagenesis 276
G05.627 Nucleic Acid Denaturation 62
G05.695 Phenotype 2 230
G05.700 Ploidies 90
G05.728 Recombination, Genetic 262
G05.755 RNA Cleavage 6
G05.762 RNA Damage
G05.769 RNA Replication
G05.783 Selection, Genetic 143
G05.810 Sequence Homology 74
G05.813 Sex Determination Processes 58
G05.815 Sex Ratio 95
G05.820 Structural Homology, Protein 30
G05.910 Sympatry 25
G05.935 Virus Integration 32

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