Interferon-Induced Helicase, IFIH1 [IFIH1]
- Terms
-
Helicard
MDA-5
MDA5
protein 5 asociovaný s diferenciací melanomu
protein obsahující helikázovou doménu C 1 a indukující interferon
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CADM-140 Autoantigen
Helicard
IFIH1 Protein
Interferon Induced with Helicase C Domain 1
Interferon-Induced Helicase C Domain-Containing Protein 1
Melanoma Differentiation-Associated Protein 5
A DEAD box RNA helicase that contains two N-terminal CASPASE ACTIVATION AND RECRUITMENT DOMAINS. It functions as a sensor of viral NUCLEIC ACIDS such as DOUBLE-STRANDED RNA and activates the INNATE IMMUNE RESPONSE by inducing the expression of INTERFERON-ALPHA and INTERFERON-BETA. It may also regulate cell growth and APOPTOSIS.
- DUI
- D000072640 MeSH Browser
- CUI
- M000617674
- Previous indexing
- DEAD-box RNA Helicases (2006-2016)
- History note
- 2017
- Public note
- 2017
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 3
- HI
- history
- IM
- immunology 2
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
IFIH1 protein, human Chemical MeSH Browser
Ifih1 protein, mouse Chemical MeSH Browser
ifih1 protein, zebrafish Chemical MeSH Browser