Interferon-Induced Helicase, IFIH1 [IFIH1]
topical
4
- Terms
-
Helicard
MDA-5
MDA5
protein 5 asociovaný s diferenciací melanomu
protein obsahující helikázovou doménu C 1 a indukující interferon
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CADM-140 Autoantigen
Helicard
IFIH1 Protein
Interferon Induced with Helicase C Domain 1
Interferon-Induced Helicase C Domain-Containing Protein 1
Melanoma Differentiation-Associated Protein 5
Persistent link
https://www.medvik.cz/link/D000072640
Definition
A DEAD box RNA helicase that contains two N-terminal CASPASE ACTIVATION AND RECRUITMENT DOMAINS. It functions as a sensor of viral NUCLEIC ACIDS such as DOUBLE-STRANDED RNA and activates the INNATE IMMUNE RESPONSE by inducing the expression of INTERFERON-ALPHA and INTERFERON-BETA. It may also regulate cell growth and APOPTOSIS.
- DUI
- D000072640 MeSH Browser
- CUI
- M000617674
- Previous indexing
- DEAD-box RNA Helicases (2006-2016)
- History note
- 2017
- Public note
- 2017
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 0
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 3
- HI
- history 0
- IM
- immunology 2
- IP
- isolation & purification 0
- ME
- metabolism 1
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs
D08.811.913.696.445.735.720.249.500
DEAD Box Protein 20
D12.776.066
Antiviral Restriction Factors
D12.776.066.032
APOBEC-3G Deaminase
D12.776.066.500
Viperin Protein