Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein [protein MALT1]
- Terms
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parakaspasa
parakaspasa MALT1
parakaspáza
parakaspáza MALT1
protein MALT-1
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MALT-1 Protein
MALT1 Paracaspase
MALT1 Protein
Paracaspase
A caspase-like cysteine endopeptidase that also exhibits ubiquitin ligase activity. It contains an N-terminal DEATH DOMAIN, two IMMUNOGLOBULIN-LIKE DOMAINS, and localizes to the perinuclear region of MONOCYTES, where it functions in activation of NF-KAPPA B; it also binds to and activates TRAF6. Chromosomal translocations involving the MALT1 and BIRC2 genes are associated with MALT LYMPHOMA, and mutations in the MALT1 gene are associated with Type 12 IMMUNODEFICIENCY SYNDROMES.
- DUI
- D000074884 MeSH Browser
- CUI
- M000628332
- Previous indexing
- Caspases (1999-2017); Neoplasm Proteins (1999-2017)
- History note
- 2018
- Public note
- 2018
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
MALT1 protein, human Chemical MeSH Browser
Malt1 protein, mouse Chemical MeSH Browser
Malt1 protein, rat Chemical MeSH Browser