protein promyelocytické leukemie s motivem zinkového prstu [Promyelocytic Leukemia Zinc Finger Protein] tematický

Termíny

protein PLZF
protein ZBTB16

 

PLZF Protein
Promyelocytic Leukaemia Zinc Finger Protein
ZBTB16 Protein
Zinc Finger and BTB Domain Containing 16 Protein

Perzistentní odkaz   https://www.medvik.cz/link/D000075722
Definice

A Kruppel-type transcription factor consisting of an N-terminal BTB DOMAIN and nine CYS2-HIS2 ZINC FINGERS. It localizes to the nucleus and regulates cell cycle progression and gene expression for tissue development and homeostasis; it may also function as an epigenetic regulator through its interactions with HISTONE DEACETYLASE. Genetic rearrangements involving the ZBTB16 gene are associated with ACUTE PROMYELOCYTIC LEUKEMIA.

DUI
D000075722
CUI
M000631303
Předchozí užití
Kruppel-Like Transcription Factors (1995-2017)
Historická pozn.
2018
Veřejná pozn.
2018