Promyelocytic Leukemia Zinc Finger Protein [protein promyelocytické leukemie s motivem zinkového prstu]

topical
4
Terms

protein PLZF
protein ZBTB16

 

PLZF Protein
Promyelocytic Leukaemia Zinc Finger Protein
ZBTB16 Protein
Zinc Finger and BTB Domain Containing 16 Protein

Definition

A Kruppel-type transcription factor consisting of an N-terminal BTB DOMAIN and nine CYS2-HIS2 ZINC FINGERS. It localizes to the nucleus and regulates cell cycle progression and gene expression for tissue development and homeostasis; it may also function as an epigenetic regulator through its interactions with HISTONE DEACETYLASE. Genetic rearrangements involving the ZBTB16 gene are associated with ACUTE PROMYELOCYTIC LEUKEMIA.

DUI
D000075722 MeSH Browser
CUI
M000631303
Previous indexing
Kruppel-Like Transcription Factors (1995-2017)
History note
2018
Public note
2018

D Chemicals and Drugs
D12.776 Proteins 2 581
D12.776.260 DNA-Binding Proteins 561
D12.776.260.522.500 Ikaros Transcription Factor 17
D12.776.260.522.532 Kruppel-Like Factor 4 4
D12.776.260.522.563 Kruppel-Like Factor 6 1
D12.776.260.522.750 Sp Transcription Factors 1
D12.776.260.522.875 Zinc Finger Protein Gli3
D12.776.930 Transcription Factors 733
D12.776.930.375.500 Ikaros Transcription Factor 17
D12.776.930.375.532 Kruppel-Like Factor 4 4
D12.776.930.375.563 Kruppel-Like Factor 6 1
D12.776.930.375.750 Sp Transcription Factors 1
D12.776.930.375.875 Zinc Finger Protein Gli3

ZBTB16 protein, human Chemical MeSH Browser

ZBTB16 protein, rat Chemical MeSH Browser

Zbtb16 protein, mouse Chemical MeSH Browser

zbtb16a protein, zebrafish Chemical MeSH Browser

zbtb16b protein, zebrafish Chemical MeSH Browser