WNK Lysine-Deficient Protein Kinase 1 [lysin-deficitní proteinkinasa WNK]
- Terms
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lysin-deficitní proteinkináza WNK
A serine-threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. It functions as an activator and inhibitor of sodium-coupled chloride co-transporters and as an inhibitor of potassium-coupled chloride co-transporters. Mutations in the WNK1 gene are associated with type 2C PSEUDOHYPOALDOSTERONISM and type 2A HEREDITARY SENSORY AND AUTONOMIC NEUROPATHIES.
- DUI
- D000076204 MeSH Browser
- CUI
- M000632439
- Previous indexing
- Intracellular Signaling Peptides and Proteins (2005-2017); Minor Histocompatibility Antigens (2005-2017); Protein-Serine-Threonine Kinases (2005-2017)
- History note
- 2018
- Public note
- 2018
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