oxaliplatin [Oxaliplatin]

tematický
26
Termíny

Eloxatin
oxaliplatina

 

1,2-Diaminocyclohexane Platinum Oxalate
1,2-Diamminocyclohexane(trans-1)oxolatoplatinum(II)
ACT 078
ACT-078
Cis-oxalato-(trans-l)-1,2-diaminocyclohexane-platinum(II)
Eloxatin
Eloxatine
L-OHP Cpd
Oxalato-(1,2-cyclohexanediamine)platinum II
Oxaliplatin, (SP-4-2-(1R-trans))-isomer
Oxaliplatin, (SP-4-2-(1S-trans))-isomer
Oxaliplatin, (SP-4-3-(cis))-isomer
Oxaliplatine
Platinum(2+) ethanedioate (1R,2R)-1,2-cyclohexanediamine (1:1:1)
Platinum(II)-1,2-cyclohexanediamine Oxalate

Perzistentní odkaz   https://www.medvik.cz/link/D000077150
Definice

An organoplatinum complex in which the platinum atom is complexed with 1,2-diaminocyclohexane, and with an oxalate ligand which is displaced to yield active oxaliplatin derivatives. These derivatives form inter- and intra-strand DNA crosslinks that inhibit DNA replication and transcription. Oxaliplatin is an antineoplastic agent that is often administered with FLUOROURACIL and FOLINIC ACID in the treatment of metastatic COLORECTAL NEOPLASMS.

DUI
D000077150 MeSH Prohlížeč
CUI
M0095550
Historická pozn.
2019 (1981)
Veřejná pozn.
2019; OXALIPLATIN was indexed under ORGANOPLATINUM COMPOUNDS 1981-2018