Crizotinib [krizotinib]
topical
51
- Terms
-
crizotinib
PF-02341066
Xalkori
-
PF 02341066
PF-02341066
PF-2341066
PF02341066
Xalkori
Persistent link
https://www.medvik.cz/link/D000077547
Definition
A piperidine and aminopyridine derivative that acts as an inhibitor of RECEPTOR PROTEIN-TYROSINE KINASES, including ANAPLASTIC LYMPHOMA KINASE (ALK) and HEPATOCYTE GROWTH FACTOR RECEPTOR (HGFR; c-Met). It is used in the treatment of NON-SMALL CELL LUNG CANCER.
- DUI
- D000077547 MeSH Browser
- CUI
- M0553416
- CAS
- 2-Pyridinamine, 3-((1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(4-piperidinyl)-1H-pyrazol-4-yl)-
- History note
- 2019 (2010)
- Public note
- 2010; CRIZOTINIB was indexed under PYRAZOLES and PYRIDINES 2010-2018
Allowable subheadings
- AD
- administration & dosage 15
- AE
- adverse effects 5
- AG
- agonists 0
- AA
- analogs & derivatives 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 1
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- EC
- economics 1
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 0
- PK
- pharmacokinetics 1
- PD
- pharmacology 13
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 29
- TO
- toxicity 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs
D03.383.621.040
Alphaprodine
D03.383.621.320
Indoramin
D03.383.621.644
Perhexiline
D03.383.621.815
Piperoxan
D03.383.725.050.920
Tripelennamine