Crizotinib [krizotinib]
topical
53
- Terms
-
crizotinib
PF-02341066
Xalkori
-
PF 02341066
PF-02341066
PF-2341066
PF02341066
Xalkori
Persistent link
https://www.medvik.cz/link/D000077547
Definition
A piperidine and aminopyridine derivative that acts as an inhibitor of RECEPTOR PROTEIN-TYROSINE KINASES, including ANAPLASTIC LYMPHOMA KINASE (ALK) and HEPATOCYTE GROWTH FACTOR RECEPTOR (HGFR; c-Met). It is used in the treatment of NON-SMALL CELL LUNG CANCER.
- DUI
- D000077547 MeSH Browser
- CUI
- M0553416
- CAS
- 2-Pyridinamine, 3-((1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(4-piperidinyl)-1H-pyrazol-4-yl)-
- History note
- 2019 (2010)
- Public note
- 2010; CRIZOTINIB was indexed under PYRAZOLES and PYRIDINES 2010-2018
Allowable subheadings
- AD
- administration & dosage 16
- AE
- adverse effects 6
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors 1
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- EC
- economics 1
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics 1
- PD
- pharmacology 15
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 31
- TO
- toxicity
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D03.383.621.040
Alphaprodine
D03.383.621.320
Indoramin
D03.383.621.644
Perhexiline
D03.383.621.815
Piperoxan
D03.383.725.050.920
Tripelennamine