Frataxin [frataxin]

topical
2
Terms

protein frataxin
protein Friedrichovy ataxie

 

Frataxin Protein
Friedreich Ataxia Protein
FXN Frataxin

Persistent link   https://www.medvik.cz/link/D000096923
Definition

A protein involved in the transfer of iron and sulfur to iron-sulfur cluster (ISC) assembly complex for de novo synthesis of a [2Fe-2S] cluster, the first step of the mitochondrial iron-sulfur protein biogenesis. Deficiency leads to the neurodegenerative disease FRIEDREICH ATAXIA.

DUI
D000096923 MeSH Browser
CUI
M000762767
History note
2024 (1996)
Public note
2024; FRATAXIN was indexed under IRON-BINDING PROTEINS 1996-2023

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics 2
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 581
D12.776.157 Carrier Proteins 546
D12.776.157.427 Iron-Binding Proteins 31
D12.776.157.427.374 Nonheme Iron Proteins 4
D12.776.157.427.374.375 Iron-Sulfur Proteins 27
D12.776.157.427.374.375.025 Adrenodoxin
D12.776.157.427.374.375.150 Ferredoxin-Nitrite Reductase
D12.776.157.427.374.375.275 Ferredoxins 14
D12.776.157.427.374.375.863 Electron Transport Complex I 44
D12.776.157.427.374.375.909 Electron Transport Complex II 20
D12.776.157.427.374.375.954 Electron Transport Complex III 19
D12.776.157.427.374.375.957 Ferrochelatase 11
D12.776.157.427.374.375.959 Frataxin 2
D12.776.157.427.374.375.960 Iron Regulatory Protein 1 1
D12.776.157.427.374.375.961 Iron Regulatory Protein 2 2
D12.776.157.427.374.375.977 Nitrate Reductase (NAD(P)H)
D12.776.157.427.374.375.988 Nitrate Reductase (NADPH) 1
D12.776.556 Metalloproteins 30
D12.776.556.579 Iron-Binding Proteins 31
D12.776.556.579.374 Nonheme Iron Proteins 4
D12.776.556.579.374.375 Iron-Sulfur Proteins 27
D12.776.556.579.374.375.025 Adrenodoxin
D12.776.556.579.374.375.140 Electron Transport Complex I 44
D12.776.556.579.374.375.141 Electron Transport Complex II 20
D12.776.556.579.374.375.142 Electron Transport Complex III 19
D12.776.556.579.374.375.150 Ferredoxin-Nitrite Reductase
D12.776.556.579.374.375.275 Ferredoxins 14
D12.776.556.579.374.375.617 Ferrochelatase 11
D12.776.556.579.374.375.789 Frataxin 2
D12.776.556.579.374.375.960 Iron Regulatory Protein 1 1
D12.776.556.579.374.375.962 Iron Regulatory Protein 2 2
D12.776.556.579.374.375.977 Nitrate Reductase (NAD(P)H)
D12.776.556.579.374.375.988 Nitrate Reductase (NADPH) 1
D12.776.575 Mitochondrial Proteins 209
D12.776.575.093 Aldehyde Dehydrogenase, Mitochondrial 5
D12.776.575.140 ATPase Inhibitory Protein
D12.776.575.186 Creatine Kinase, Mitochondrial Form 3
D12.776.575.280 DNA Polymerase gamma 3
D12.776.575.374 Endopeptidase Clp
D12.776.575.562 Ferrochelatase 11
D12.776.575.609 Frataxin 2
D12.776.575.656 High-Temperature Requirement A Serine Peptidase 2
D12.776.575.750 Mitochondrial Membrane Transport Proteins 35
D12.776.575.758 Mitochondrial Processing Peptidase
D12.776.575.765 Mitochondrial Trifunctional Protein 2
D12.776.575.781 Nucleoside Diphosphate Kinase D
D12.776.575.812 Peroxiredoxin III 2
D12.776.575.844 Prohibitins 1
D12.776.575.875 Sirtuin 3 5

FXN protein, human Chemical MeSH Browser

Fxn protein, mouse Chemical MeSH Browser

YFH1 protein, S cerevisiae Chemical MeSH Browser

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