Amanitins [amanitiny]
- Terms
-
Amanitin
Cyclic peptides extracted from carpophores of various mushroom species. They are potent inhibitors of RNA polymerases in most eukaryotic species, blocking the production of mRNA and protein synthesis. These peptides are important in the study of transcription. Alpha-amanitin is the main toxin from the species Amanitia phalloides, poisonous if ingested by humans or animals.
- Annotation
- /antag permitted but consider also ANTITOXINS
- DUI
- D000546 MeSH Browser
- CUI
- M0000846
- Previous indexing
- Mycotoxins (1974); Oligopeptides (1974); Peptides, Cyclic (1974)
- History note
- 75
- Public note
- 75
Allowable subheadings
- AD
- administration & dosage 1
- AE
- adverse effects 1
- AG
- agonists
- AN
- analysis 8
- AI
- antagonists & inhibitors 1
- BI
- biosynthesis
- BL
- blood 1
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology 4
- PH
- physiology 1
- PO
- poisoning 8
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity 6
- UR
- urine 3
2-methyl-demethyl gamma-amanitin Chemical MeSH Browser
6'-O-methyl alpha-amanitin Chemical MeSH Browser
7-nitrobenz-2-oxa-1,3-diazole-phallacidin Chemical MeSH Browser
Ala(7)-phalloidin Chemical MeSH Browser
aldoamanitin Chemical MeSH Browser
alpha-amanitinylazobenzoylglycylglycine Chemical MeSH Browser
amaninamide Chemical MeSH Browser
amaninamide, Ile(3)- Chemical MeSH Browser
amaninamide, S-deoxo-Abu(1)-Ile(3)- Chemical MeSH Browser
amaninamide, S-deoxy-(gamma-hydroxy-Ile(3))- Chemical MeSH Browser
amaninamide, deoxy-Ile(3)-Ala(5)- Chemical MeSH Browser
amaninamide, deoxy-Ile(3)-Ala(7)- Chemical MeSH Browser
amatoxin Chemical MeSH Browser
beta-amanitin Chemical MeSH Browser
phallolysine Chemical MeSH Browser
phallotoxin Chemical MeSH Browser