Histocompatibility Antigens Class II [MHC antigeny II. třídy]
- Terms
-
antigeny imunitní odpovědi
histokompatibilita - antigeny třídy II
MHC glykoproteiny II. třídy
MHC molekuly II. třídy
molekuly MHC II
-
Antigens, Immune Response
Class II Antigen
Class II Antigens
Class II Histocompatibility Antigen
Class II Histocompatibility Antigens
Class II Major Histocompatibility Antigen
Class II Major Histocompatibility Antigens
Class II Major Histocompatibility Molecules
Class II MHC Proteins
I-A Antigen
I-A-Antigen
IA Antigen
Ia Antigens
Ia-Like Antigen
Ia-Like Antigens
Immune Response Antigens
Immune-Associated Antigens
Immune-Response-Associated Antigens
MHC Class II Molecule
MHC Class II Molecules
MHC II Peptide
MHC II Peptides
MHC-II Molecules
Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural variation in the beta chains. The class II antigens in humans are called HLA-D ANTIGENS and are coded by a gene on chromosome 6. In mice, two genes named IA and IE on chromosome 17 code for the H-2 antigens. The antigens are found on B-lymphocytes, macrophages, epidermal cells, and sperm and are thought to mediate the competence of and cellular cooperation in the immune response. The term IA antigens used to refer only to the proteins encoded by the IA genes in the mouse, but is now used as a generic term for any class II histocompatibility antigen.
- Annotation
- human & animal; see also HLA ANTIGENS & specifics for human
- DUI
- D000949 MeSH Browser
- CUI
- M0001420
- Previous indexing
- Histocompatibility Antigens (1973-1980); HLA Antigens (1975-1980); Isoantigens (1973-1980)
- History note
- 1989 (1973); use ANTIGENS, IMMUNE RESPONSE 1981-88
- Public note
- 1989; see ANTIGENS, IMMUNE RESPONSE 1981-88
Allowable subheadings
- AD
- administration & dosage 0
- AN
- analysis 6
- BI
- biosynthesis 1
- BL
- blood 1
- CF
- cerebrospinal fluid 0
- CH
- chemistry 1
- CL
- classification 0
- DE
- drug effects 2
- EC
- economics 0
- GE
- genetics 27
- HI
- history 0
- IM
- immunology 23
- IP
- isolation & purification 0
- ME
- metabolism 8
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0