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benzopyrenhydroxylasa [Benzopyrene Hydroxylase]

tematický
Termíny

benzopyrenhydroxyláza

 

Benzo(a)pyrene Hydroxylase
Benzo(a)pyrene Monooxygenase
Benzopyrene-3-Monooxygenase

Perzistentní odkaz   https://www.medvik.cz/link/D001579
Definice

Enzym cytochromu P-448 (P-450) metabolizující léky, který katalyzuje hydroxylaci benzopyrenu na 3-hydroxybenzopyren v přítomnosti redukovaného flavoproteinu a molekulárního kyslíku. Působí také na určité deriváty anthracenu.

A drug-metabolizing, cytochrome P-448 (P-450) enzyme which catalyzes the hydroxylation of benzopyrene to 3-hydroxybenzopyrene in the presence of reduced flavoprotein and molecular oxygen. Also acts on certain anthracene derivatives. An aspect of EC 1.14.14.1.

Anotace
a cytochrome
DUI
D001579 MeSH Prohlížeč
CUI
M0002368
Předchozí užití
Benzopyrenes (1968-1974); Hydroxylases (1968-1974)
Historická pozn.
91(75); was see under ARYL HYDROCARBON HYDROXYLASES 1977-90; was see under HYDROXYLASES 1975-76
Veřejná pozn.
91; was see under ARYL HYDROCARBON HYDROXYLASES 1977-90; was see under HYDROXYLASES 1975-76

Povolená podhesla

AN
analýza
AI
antagonisté a inhibitory
AD
aplikace a dávkování
BI
biosyntéza
CS
chemická syntéza
CH
chemie
HI
dějiny
EC
ekonomika
PK
farmakokinetika
PD
farmakologie
PH
fyziologie
GE
genetika
IM
imunologie
IP
izolace a purifikace
CL
klasifikace
BL
krev
ME
metabolismus
UR
moč
CF
mozkomíšní mok
DF
nedostatek
ST
normy
PO
otrava
AE
škodlivé účinky
TU
terapeutické užití
TO
toxicita
DE
účinky léků
RE
účinky záření
UL
ultrastruktura
SD
zásobování a distribuce

D Chemikálie a léčiva
D08 enzymy a koenzymy 7
D08.244 cytochromy 121
D08.244.453 systém (enzymů) cytochromů P-450 696
D08.244.453.005 aromatické hydroxylasy 80
D08.244.453.005.050 anilinhydroxylasa 1
D08.244.453.005.110 benzopyrenhydroxylasa
D08.244.453.005.332 cytochrom P-450 CYP1A1 172
D08.244.453.005.443 cytochrom P-450 CYP1A2 72
D08.244.453.005.500 cytochrom P450 CYP1B1 9
D08.244.453.005.550 cytochrom P-450 CYP2B1 4
D08.244.453.005.575 cytochrom P450 CYP2B6 9
D08.244.453.005.590 cytochrom P450 CYP2C8 8
D08.244.453.005.600 cytochrom P-450 CYP2D6 122
D08.811 enzymy 1 554
D08.811.682 oxidoreduktasy 448
D08.811.682.690 oxygenasy 77
D08.811.682.690.708 oxygenasy se smíšenou funkcí 68
D08.811.682.690.708.170 systém (enzymů) cytochromů P-450 696
D08.811.682.690.708.170.010 aromatické hydroxylasy 80
D08.811.682.690.708.170.010.024 7-alkoxykumarin-O-dealkylasa
D08.811.682.690.708.170.010.050 anilinhydroxylasa 1
D08.811.682.690.708.170.010.110 benzopyrenhydroxylasa
D08.811.682.690.708.170.010.277 cytochrom P-450 CYP1A1 172
D08.811.682.690.708.170.010.443 cytochrom P-450 CYP1A2 72
D08.811.682.690.708.170.010.500 cytochrom P450 CYP1B1 9
D08.811.682.690.708.170.010.550 cytochrom P-450 CYP2B1 4
D08.811.682.690.708.170.010.575 cytochrom P450 CYP2B6 9
D08.811.682.690.708.170.010.590 cytochrom P450 CYP2C8 8
D08.811.682.690.708.170.010.600 cytochrom P-450 CYP2D6 122
D12 aminokyseliny, peptidy a proteiny 16
D12.776 proteiny 2 587
D12.776.422 hemoproteiny 16
D12.776.422.220 cytochromy 121
D12.776.422.220.453 systém (enzymů) cytochromů P-450 696
D12.776.422.220.453.010 aromatické hydroxylasy 80
D12.776.422.220.453.010.050 anilinhydroxylasa 1
D12.776.422.220.453.010.110 benzopyrenhydroxylasa
D12.776.422.220.453.010.332 cytochrom P-450 CYP1A1 172
D12.776.422.220.453.010.443 cytochrom P-450 CYP1A2 72
D12.776.422.220.453.010.500 cytochrom P450 CYP1B1 9
D12.776.422.220.453.010.550 cytochrom P-450 CYP2B1 4
D12.776.422.220.453.010.575 cytochrom P450 CYP2B6 9
D12.776.422.220.453.010.590 cytochrom P450 CYP2C8 8
D12.776.422.220.453.010.600 cytochrom P-450 CYP2D6 122

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