Coproporphyrinogen Oxidase [koproporfyrinogenoxidasa]
- Terms
-
koproporfyrinogenoxidáza
-
Coproporphyrinogen III Oxidases
Coproporphyrinogenase
An enzyme that catalyzes the oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX by the conversion of two propionate groups to two vinyl groups. It is the sixth enzyme in the 8-enzyme biosynthetic pathway of HEME, and is encoded by CPO gene. Mutations of CPO gene result in HEREDITARY COPROPORPHYRIA.
- DUI
- D003304 MeSH Browser
- CUI
- M0005157
- CAS
- Coproporphyrinogen:oxygen oxidoreductase (decarboxylating)
- Previous indexing
- Carboxy-Lyases (1972-1974); Coproporphyrins (1975); Oxidoreductases (1975); Porphyrins (1972-1974)
- History note
- 91(76); was see under OXIDOREDUCTASES 1976-90
- Public note
- 91; was see under OXIDOREDUCTASES 1976-90
Combination
- deficiency
- Coproporphyria, Hereditary
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis 1
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 1
- CL
- classification
- DE
- drug effects
- EC
- economics
- GE
- genetics 1
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
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