Enzym katalyzující přeměnu koproporfyrinogenu III na protoporfyrinogen IX. Gen je na 3. chromozomu. Mutace způsobují hereditární koproporfyrii. (cit. Velký lékařský slovník online, 2017 http://lekarske.slovniky.cz)

An enzyme that catalyzes the oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX by the conversion of two propionate groups to two vinyl groups. It is the sixth enzyme in the 8-enzyme biosynthetic pathway of HEME, and is encoded by CPO gene. Mutations of CPO gene result in HEREDITARY COPROPORPHYRIA.

DUI

D003304 MeSH Prohlížeč

CUI

M0005157

RN

EC 1.3.3.3

CAS

Coproporphyrinogen:oxygen oxidoreductase (decarboxylating)

Předchozí užití

Carboxy-Lyases (1972-1974); Coproporphyrins (1975); Oxidoreductases (1975); Porphyrins (1972-1974)

Historická pozn.

91(76); was see under OXIDOREDUCTASES 1976-90

Veřejná pozn.

91; was see under OXIDOREDUCTASES 1976-90