Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase [lysinhydroxylasa]

topical
2
Terms

lysylhydroxylasa
lysylhydroxyláza
lyzinhydroxyláza
lyzylhydroxyláza

 

Collagen Lysyl Hydroxylase
Lysine 2-Oxoglutarate Dioxygenase
Lysine Hydroxylase
Lysyl Hydroxylase
Protocollagen Lysyl Hydroxylase

Persistent link   https://www.medvik.cz/link/D008240
Definition

A mixed-function oxygenase that catalyzes the hydroxylation of peptidyllysine, usually in protocollagen, to peptidylhydroxylysine. The enzyme utilizes molecular oxygen with concomitant oxidative decarboxylation of the cosubstrate 2-oxoglutarate to succinate. EC 1.14.11.4.

DUI
D008240 MeSH Browser
CUI
M0012838
CAS
Procollagen-L-lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating)
Previous indexing
Lysine (1966-1976); Hydroxylases (1966-1976); Ketoglutaric Acids (1966-1976)
History note
92; was LYSINE HYDROXYLASE 1977-91 (see under HYDROXYLASES 1977-90)
Online note
use PROCOLLAGEN-LYSINE, 2-OXOGLUTARATE 5-DIOXYGENASE to search LYSINE HYDROXYLASE 1977-91
Public note
92; was LYSINE HYDROXYLASE 1977-91 (see under HYDROXYLASES 1977-90)

D Chemicals and Drugs
D08.811 Enzymes 1 551
D08.811.682 Oxidoreductases 446
D08.811.682.690 Oxygenases 76
D08.811.682.690.708 Mixed Function Oxygenases 68
D08.811.682.690.708.062 Benzoate 4-Monooxygenase
D08.811.682.690.708.125 Catechol Oxidase 15
D08.811.682.690.708.170 Cytochrome P-450 Enzyme System 692
D08.811.682.690.708.292 Dopamine beta-Hydroxylase 52
D08.811.682.690.708.392 Fatty Acid Desaturases 44
D08.811.682.690.708.401 gamma-Butyrobetaine Dioxygenase
D08.811.682.690.708.410 Heme Oxygenase (Decyclizing) 24
D08.811.682.690.708.425 4-Hydroxybenzoate-3-Monooxygenase
D08.811.682.690.708.557 Kynurenine 3-Monooxygenase 1
D08.811.682.690.708.601 Phenylalanine Hydroxylase 27
D08.811.682.690.708.694 Prolyl Hydroxylases 1
D08.811.682.690.708.715 Prostaglandin-Endoperoxide Synthases 40
D08.811.682.690.708.749 Squalene Monooxygenase
D08.811.682.690.708.826 Trans-Cinnamate 4-Monooxygenase 1
D08.811.682.690.708.870 Tryptophan Hydroxylase 3
D08.811.682.690.708.923 Tyrosine 3-Monooxygenase 49
D08.811.682.690.708.961 Vitamin K Epoxide Reductases 7
D10 Lipids 2 528

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