A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA.

DUI

D008466 MeSH Browser

CUI

M0013168

CAS

Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl-

History note

MECHLORETHAMINE OXIDE was heading 1963-79; NITROGEN MUSTARD N-OXIDE was NITROGEN MUSTARD N-OXIDE (NM) 1984-91

Online note

use MECHLORETHAMINE to search MECHLORETHAMINE OXIDE 1966-79; use MECHLORETHAMINE (NM) to search NITROGEN MUSTARD N-OXIDE (NM) 1984-91

Public note

MECHLORETHAMINE OXIDE was heading 1963-79; NITROGEN MUSTARD N-OXIDE was indexed under NITROGEN MUSTARD COMPOUNDS 1984-91