Masoprocol [kyselina nordihydroguaiaretová]
- Terms
-
masoprokol
-
(R*,S*)-4,4'-(2,3-Dimethylbutane-1,4-diyl)bispyrocatechol
Actinex
Dihydronorguaiaretic Acid
meso-Nordihydroguaiaretic Acid
Nordihydroguaiaretic Acid
Nordihydroguaiaretic Acid, (R*,S*)-Isomer
A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils.
- DUI
- D009637 MeSH Browser
- CUI
- M0014961
- CAS
- 1,2-Benzenediol, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-
- Previous indexing
- Catechols (1966-1986)
- History note
- 2014(1987)
- Public note
- 2014; see NORDIHYDROGUAIARETIC ACID 1991-2013; see CATECHOLS 1987-1990
Allowable subheadings
- AD
- administration & dosage 2
- AE
- adverse effects
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology 4
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UR
- urine