Pyrrolizidine Alkaloids [pyrrolizidinové alkaloidy]
topical
17
- Terms
-
Pyrrolizidine Alkaloid
Senecio Alkaloid
Senecio Alkaloids
Persistent link
https://www.medvik.cz/link/D011763
Definition
A group of ALKALOIDS, characterized by a nitrogen-containing necine, occurring mainly in plants of the BORAGINACEAE; COMPOSITAE; and LEGUMINOSAE plant families. They can be activated in the liver by hydrolysis of the ester and desaturation of the necine base to reactive electrophilic pyrrolic CYTOTOXINS.
- DUI
- D011763 MeSH Browser
- CUI
- M0018283
- Previous indexing
- Heterocyclic Compounds (1966-1970); Alkaloids (1966-1970)
- History note
- 73(71)
- Public note
- 73
Allowable subheadings
- AD
- administration & dosage 2
- AE
- adverse effects 3
- AG
- agonists 0
- AN
- analysis 1
- AI
- antagonists & inhibitors 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 1
- CH
- chemistry 2
- CL
- classification 0
- EC
- economics 0
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 1
- ME
- metabolism 2
- PK
- pharmacokinetics 1
- PD
- pharmacology 1
- PO
- poisoning 1
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 2
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs
D03.132.032
Acridones
D03.132.285
Dihydro-beta-Erythroidine
D03.132.301
Diterpene Alkaloids
D03.132.795
Stemona Alkaloids
D03.633.100.673
Piperoxan