RNA-Directed DNA Polymerase [reverzní transkriptasa]

topical
45
Terms

reverzní transkriptáza
RNA dependentní DNA polymerasa
RNA dependentní DNA polymeráza
RNA řízená DNA polymerasa
RNA řízená DNA polymeráza

 

DNA Polymerase, RNA-Directed
Reverse Transcriptase
Revertase
RNA Transcriptase
RNA-Dependent DNA Polymerase

Persistent link   https://www.medvik.cz/link/D012194
Definition

An enzyme that synthesizes DNA on an RNA template. It is encoded by the pol gene of retroviruses and by certain retrovirus-like elements. EC 2.7.7.49.

DUI
D012194 MeSH Browser
CUI
M0018988
CAS
Deoxynucleotide-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed)
Previous indexing
DNA Nucleotidyltransferases (1968-1971)
History note
96; was REVERSE TRANSCRIPTASE 1972-95 (Prov 1972)
Public note
96; was REVERSE TRANSCRIPTASE 1973-95

Combination

antagonists & inhibitors
Reverse Transcriptase Inhibitors

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AN
analysis 1
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 2
CL
classification 1
DF
deficiency
DE
drug effects 1
EC
economics
GE
genetics 8
HI
history 1
IM
immunology 1
IP
isolation & purification
ME
metabolism 6
PK
pharmacokinetics
PD
pharmacology 1
PH
physiology 3
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 547
D08.811.913 Transferases 72
D08.811.913.696 Phosphotransferases 69
D08.811.913.696.445 Nucleotidyltransferases 15
D08.811.913.696.445.308 DNA Nucleotidyltransferases 6
D08.811.913.696.445.308.300 DNA-Directed DNA Polymerase 62
D08.811.913.696.445.308.300.112 DNA Polymerase beta 1
D08.811.913.696.445.308.300.169 DNA Polymerase gamma 3
D08.811.913.696.445.308.300.225 DNA Polymerase I 9
D08.811.913.696.445.308.300.230 DNA Polymerase II 5
D08.811.913.696.445.308.300.235 DNA Polymerase III 7
D08.811.913.696.445.308.300.493 DNA Polymerase iota
D08.811.913.696.445.308.300.622 DNA Polymerase theta
D08.811.913.696.445.308.300.750 RNA-Directed DNA Polymerase 45
D08.811.913.696.445.308.300.750.187 HIV Reverse Transcriptase 9
D08.811.913.696.445.308.300.750.750 Telomerase 189
D08.811.913.696.445.308.300.875 Taq Polymerase 4
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 577
D12.776.964 Viral Proteins 375
D12.776.964.775 Retroviridae Proteins 10
D12.776.964.775.375 Gene Products, pol 1
D12.776.964.775.375.325 Fusion Proteins, gag-pol 1
D12.776.964.775.375.545 pol Gene Products, Human Immunodeficiency Virus 1
D12.776.964.775.375.750 RNA-Directed DNA Polymerase 45
D12.776.964.775.375.750.187 HIV Reverse Transcriptase 9
D12.776.964.900 Viral Nonstructural Proteins 44
D12.776.964.900.750 Viral Replicase Complex Proteins
D12.776.964.900.750.500 Gene Products, pol 1
D12.776.964.900.750.500.325 Fusion Proteins, gag-pol 1
D12.776.964.900.750.500.545 pol Gene Products, Human Immunodeficiency Virus 1
D12.776.964.900.750.500.750 RNA-Directed DNA Polymerase 45
D12.776.964.900.750.500.750.187 HIV Reverse Transcriptase 9
D12.776.964.970 Viral Structural Proteins 16
D12.776.964.970.600 Nucleocapsid Proteins 15
D12.776.964.970.600.850 Viral Core Proteins 12
D12.776.964.970.600.850.375 Gene Products, pol 1
D12.776.964.970.600.850.375.325 Fusion Proteins, gag-pol 1
D12.776.964.970.600.850.375.545 pol Gene Products, Human Immunodeficiency Virus 1
D12.776.964.970.600.850.375.750 RNA-Directed DNA Polymerase 45
D12.776.964.970.600.850.375.750.187 HIV Reverse Transcriptase 9

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