tosylfenylalanylchlormethylketon [Tosylphenylalanyl Chloromethyl Ketone]

tematický
4
Termíny

Chlorophenyltosylamidobutanone
Tosylphenylalanyl Chloromethane
TPCK

Perzistentní odkaz   https://www.medvik.cz/link/D014108
Definice

Inhibitor serinových endopeptidáz. Působí jako alkylační činidlo a je známo, že interferuje s procesem translace.

An inhibitor of Serine Endopeptidases. Acts as alkylating agent and is known to interfere with the translation process.

DUI
D014108 MeSH Prohlížeč
CUI
M0021715
CAS
Benzenesulfonamide, N-(3-chloro-2-oxo-1-(phenylmethyl)propyl)-4-methyl-, (S)-
Předchozí užití
Tosyl Compounds (1973-1974); Phenylalanine (1972-1974); Chlorine (1974)
Historická pozn.
91(75); was see under AMINO ACID CHLOROMETHYL KETONES 1977-90; was see under PHENYLALANINE 1975-76
Veřejná pozn.
91; was see under AMINO ACID CHLOROMETHYL KETONES 1977-90; was see under PHENYLALANINE 1975-76

Povolená podhesla

AG
agonisté
AA
analogy a deriváty
AN
analýza
AI
antagonisté a inhibitory
AD
aplikace a dávkování
CS
chemická syntéza
CH
chemie
HI
dějiny
EC
ekonomika
PK
farmakokinetika
PD
farmakologie 4
IM
imunologie
IP
izolace a purifikace
CL
klasifikace
BL
krev
ME
metabolismus
UR
moč
CF
mozkomíšní mok
ST
normy
PO
otrava
AE
škodlivé účinky
TU
terapeutické užití
TO
toxicita
RE
účinky záření
SD
zásobování a distribuce

D Chemikálie a léčiva
D02 organické látky 391
D02.065 amidy 259
D02.065.884 sulfonamidy 767
D02.065.884.060 benzensulfonamidy 2
D02.065.884.060.003 acetohexamid
D02.065.884.060.005 bosentan 16
D02.065.884.060.010 karbutamid 2
D02.065.884.060.020 celekoxib 13
D02.065.884.060.040 chlorpropamid 9
D02.065.884.060.050 chlorthalidon 41
D02.065.884.060.100 gliklazid 63
D02.065.884.060.150 mafenid 1
D02.065.884.060.160 sulfachlorpyridazin
D02.065.884.060.170 sulfadiazin 28
D02.065.884.060.180 sulfadimethoxin 3
D02.065.884.060.190 sulfadoxin 4
D02.065.884.060.200 sulfaguanidin 3
D02.065.884.060.210 sulfalen
D02.065.884.060.220 sulfamerazin 2
D02.065.884.060.230 sulfametr 4
D02.065.884.060.240 sulfamethazin 14
D02.065.884.060.250 sulfamethizol 1
D02.065.884.060.300 sulfamethoxazol 31
D02.065.884.060.325 sulfamethoxypyridazin 9
D02.065.884.060.338 sulfamonomethoxin 2
D02.065.884.060.344 sulfamoxol
D02.065.884.060.350 sulfanilamid 1
D02.065.884.060.400 sulfafenazol 3
D02.065.884.060.450 sulfapyridin 4
D02.065.884.060.500 sulfachinoxalin
D02.065.884.060.550 sulfathiazol 2
D02.065.884.060.600 sulfisomidin 1
D02.065.884.060.650 sulfisoxazol 5
D02.065.884.060.700 tamsulosin 14
D02.065.884.060.740 tolazamid
D02.065.884.060.745 tolbutamid 57
D02.065.884.060.872 tosyllysinchlormethylketon 4
D02.065.884.060.936 tosylfenylalanylchlormethylketon 4
D02.455 uhlovodíky 139
D02.455.426 cyklické uhlovodíky 24
D02.455.426.559 aromatické uhlovodíky 50
D02.455.426.559.389 benzenové deriváty 73
D02.455.426.559.389.085 benzensulfonamidy 2
D02.455.426.559.389.085.003 acetohexamid
D02.455.426.559.389.085.005 bosentan 16
D02.455.426.559.389.085.010 karbutamid 2
D02.455.426.559.389.085.020 celekoxib 13
D02.455.426.559.389.085.040 chlorpropamid 9
D02.455.426.559.389.085.050 chlorthalidon 41
D02.455.426.559.389.085.100 gliklazid 63
D02.455.426.559.389.085.150 mafenid 1
D02.455.426.559.389.085.160 sulfachlorpyridazin
D02.455.426.559.389.085.170 sulfadiazin 28
D02.455.426.559.389.085.180 sulfadimethoxin 3
D02.455.426.559.389.085.190 sulfadoxin 4
D02.455.426.559.389.085.200 sulfaguanidin 3
D02.455.426.559.389.085.210 sulfalen
D02.455.426.559.389.085.220 sulfamerazin 2
D02.455.426.559.389.085.230 sulfametr 4
D02.455.426.559.389.085.240 sulfamethazin 14
D02.455.426.559.389.085.250 sulfamethizol 1
D02.455.426.559.389.085.300 sulfamethoxazol 31
D02.455.426.559.389.085.325 sulfamethoxypyridazin 9
D02.455.426.559.389.085.338 sulfamonomethoxin 2
D02.455.426.559.389.085.344 sulfamoxol
D02.455.426.559.389.085.350 sulfanilamid 1
D02.455.426.559.389.085.400 sulfafenazol 3
D02.455.426.559.389.085.450 sulfapyridin 4
D02.455.426.559.389.085.500 sulfachinoxalin
D02.455.426.559.389.085.550 sulfathiazol 2
D02.455.426.559.389.085.600 sulfisomidin 1
D02.455.426.559.389.085.650 sulfisoxazol 5
D02.455.426.559.389.085.700 tamsulosin 14
D02.455.426.559.389.085.740 tolazamid
D02.455.426.559.389.085.745 tolbutamid 57
D02.455.426.559.389.085.872 tosyllysinchlormethylketon 4
D02.455.426.559.389.085.936 tosylfenylalanylchlormethylketon 4
D02.455.426.559.389.832 toluen 210
D02.455.426.559.389.832.140 bromkresolová zeleň 3
D02.455.426.559.389.832.150 bromkresolová červeň 2
D02.455.426.559.389.832.180 bromfenolová modř 3
D02.455.426.559.389.832.200 bromthymolová modř 3
D02.455.426.559.389.832.500 toluendiisokyanát 12
D02.455.426.559.389.832.559 toluidiny 76
D02.455.426.559.389.832.661 tosylové sloučeniny 23
D02.455.426.559.389.832.670 tosylargininmethylester 2
D02.455.426.559.389.832.690 tosyllysinchlormethylketon 4
D02.455.426.559.389.832.710 tosylfenylalanylchlormethylketon 4
D02.455.426.559.389.832.767 trifluralin 2
D02.455.426.559.389.832.868 trinitrotoluen 20
D02.886 sloučeniny síry 42
D02.886.590 sulfony 122
D02.886.590.700 sulfonamidy 767
D02.886.590.700.090 benzensulfonamidy 2
D02.886.590.700.090.003 acetohexamid
D02.886.590.700.090.005 bosentan 16
D02.886.590.700.090.010 karbutamid 2
D02.886.590.700.090.020 celekoxib 13
D02.886.590.700.090.040 chlorpropamid 9
D02.886.590.700.090.050 chlorthalidon 41
D02.886.590.700.090.100 gliklazid 63
D02.886.590.700.090.150 mafenid 1
D02.886.590.700.090.160 sulfachlorpyridazin
D02.886.590.700.090.170 sulfadiazin 28
D02.886.590.700.090.180 sulfadimethoxin 3
D02.886.590.700.090.190 sulfadoxin 4
D02.886.590.700.090.200 sulfaguanidin 3
D02.886.590.700.090.210 sulfalen
D02.886.590.700.090.220 sulfamerazin 2
D02.886.590.700.090.230 sulfametr 4
D02.886.590.700.090.240 sulfamethazin 14
D02.886.590.700.090.250 sulfamethizol 1
D02.886.590.700.090.300 sulfamethoxazol 31
D02.886.590.700.090.325 sulfamethoxypyridazin 9
D02.886.590.700.090.338 sulfamonomethoxin 2
D02.886.590.700.090.344 sulfamoxol
D02.886.590.700.090.350 sulfanilamid 1
D02.886.590.700.090.400 sulfafenazol 3
D02.886.590.700.090.450 sulfapyridin 4
D02.886.590.700.090.500 sulfachinoxalin
D02.886.590.700.090.550 sulfathiazol 2
D02.886.590.700.090.600 sulfisomidin 1
D02.886.590.700.090.650 sulfisoxazol 5
D02.886.590.700.090.700 tamsulosin 14
D02.886.590.700.090.740 tolazamid
D02.886.590.700.090.745 tolbutamid 57
D02.886.590.700.090.872 tosyllysinchlormethylketon 4
D02.886.590.700.090.936 tosylfenylalanylchlormethylketon 4
D02.886.590.887 tosylové sloučeniny 23
D02.886.590.887.140 bromkresolová zeleň 3
D02.886.590.887.150 bromkresolová červeň 2
D02.886.590.887.180 bromfenolová modř 3
D02.886.590.887.200 bromthymolová modř 3
D02.886.590.887.570 tosylargininmethylester 2
D02.886.590.887.600 tosyllysinchlormethylketon 4
D02.886.590.887.660 tosylfenylalanylchlormethylketon 4
D12 aminokyseliny, peptidy a proteiny 16
D12.125 aminokyseliny 1 357
D12.125.065 chloromethylketony aminokyselin 11
D12.125.065.850 tosyllysinchlormethylketon 4
D12.125.065.930 tosylfenylalanylchlormethylketon 4

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