komplement C5a [Complement C5a]

tematický
3
Termíny

komplement 5a

 

C5a Complement
Complement 5a
Complement Component 5a

Perzistentní odkaz   https://www.medvik.cz/link/D015936
Definice

The minor fragment formed when C5 convertase cleaves C5 into C5a and COMPLEMENT C5B. C5a is a 74-amino-acid glycopeptide with a carboxy-terminal ARGININE that is crucial for its spasmogenic activity. Of all the complement-derived anaphylatoxins, C5a is the most potent in mediating immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE), smooth MUSCLE CONTRACTION; HISTAMINE RELEASE; and migration of LEUKOCYTES to site of INFLAMMATION.

DUI
D015936 MeSH Prohlížeč
CUI
M0024381
CAS
Complement C5a
Předchozí užití
Anaphylatoxins (1977-1989); Complement (1972-1975); Complement 5 (1975-1989)
Historická pozn.
2006 (1990)
Veřejná pozn.
2006; see COMPLEMENT 5A 1990-2005

D Chemikálie a léčiva
D12.776 proteiny 2 575
D12.776.124 krevní proteiny 909
D12.776.124.486 imunoproteiny 14
D12.776.124.486.274 komplement 351
D12.776.124.486.274.024 anafylatoxiny 6
D12.776.124.486.274.024.250 komplement C3a 3
D12.776.124.486.274.024.260 komplement C4a 1
D12.776.124.486.274.024.270 komplement C5a 3
D12.776.124.486.274.024.270.255 komplement C5a desargininový
D12.776.124.486.274.450 komplement C5 26
D12.776.124.486.274.450.250 komplement C5a 3
D12.776.124.486.274.450.250.255 komplement C5a desargininový
D12.776.124.486.274.450.625 komplement C5b