Genes, Retinoblastoma [geny retinoblastomu]

topical
15
Terms

gen Rb
gen retinoblastomu
Rb gen
Rb geny

 

Genes, Rb
Rb Genes
Retinoblastoma Genes

Persistent link   https://www.medvik.cz/link/D016161
Definition

Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma.

DUI
D016161 MeSH Browser
CUI
M0024674
Previous indexing
Retinoblastoma/genetics (1972-1990)
History note
91
Public note
91

Allowable subheadings

DE
drug effects 0
ES
ethics 0
GE
genetics 2
IM
immunology 0
PH
physiology 2
RE
radiation effects 0

G Phenomena and Processes
G05 Genetic Phenomena 135
G05.360 Genetic Structures 25
G05.360.340 Genome 361
G05.360.340.024 Genome Components 13
G05.360.340.024.340 Genes 673
G05.360.340.024.340.375 Genes, Neoplasm 34
G05.360.340.024.340.375.249 Genes, Tumor Suppressor 165
G05.360.340.024.340.375.249.050 Genes, APC 40
G05.360.340.024.340.375.249.100 Genes, BRCA1 280
G05.360.340.024.340.375.249.105 Genes, BRCA2 248
G05.360.340.024.340.375.249.200 Genes, DCC 2
G05.360.340.024.340.375.249.320 Genes, MCC
G05.360.340.024.340.375.249.340 Genes, Neurofibromatosis 1 14
G05.360.340.024.340.375.249.345 Genes, Neurofibromatosis 2 1
G05.360.340.024.340.375.249.375 Genes, p16 20
G05.360.340.024.340.375.249.385 Genes, p53 263
G05.360.340.024.340.375.249.400 Genes, Retinoblastoma 15
G05.360.340.024.340.375.249.420 Genes, Wilms Tumor 20
G05.360.340.024.340.415 Genes, Recessive 49
G05.360.340.024.340.415.400 Genes, Tumor Suppressor 165
G05.360.340.024.340.415.400.050 Genes, APC 40
G05.360.340.024.340.415.400.100 Genes, BRCA1 280
G05.360.340.024.340.415.400.105 Genes, BRCA2 248
G05.360.340.024.340.415.400.200 Genes, DCC 2
G05.360.340.024.340.415.400.320 Genes, MCC
G05.360.340.024.340.415.400.340 Genes, Neurofibromatosis 1 14
G05.360.340.024.340.415.400.345 Genes, Neurofibromatosis 2 1
G05.360.340.024.340.415.400.375 Genes, p16 20
G05.360.340.024.340.415.400.385 Genes, p53 263
G05.360.340.024.340.415.400.400 Genes, Retinoblastoma 15
G05.360.340.024.340.415.400.420 Genes, Wilms Tumor 20

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