Lymphocyte Function-Associated Antigen-1 [antigen-1 spojený s lymfocytární funkcí]
topical
7
- Terms
-
Integrin alphaLbeta2
Leukocyte Function Associated Antigen-1
LFA-1
Persistent link
https://www.medvik.cz/link/D016169
Definition
An integrin heterodimer widely expressed on cells of hematopoietic origin. CD11A ANTIGEN comprises the alpha chain and the CD18 antigen (CD18 ANTIGENS) the beta chain. Lymphocyte function-associated antigen-1 is a major receptor of T-CELLS; B-CELLS; and GRANULOCYTES. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by NATURAL KILLER CELLS and granulocytes. Intracellular adhesion molecule-1 has been defined as a ligand for lymphocyte function-associated antigen-1.
- DUI
- D016169 MeSH Browser
- CUI
- M0024683
- Previous indexing
- Antigens, Differentiation (1988-1990); Receptors, Leukocyte-Adhesion (1989-1990)
- History note
- 1991
- Public note
- 1991
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CH
- chemistry 1
- CL
- classification
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology 2
- IP
- isolation & purification
- ME
- metabolism 2
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records