A work that reports on a clinical trial involving one or more test treatments, at least one control treatment, specified outcome measures for evaluating the studied intervention, and a bias-free method for assigning patients to the test treatment. The treatment may be drugs, devices, or procedures studied for diagnostic, therapeutic, or prophylactic effectiveness. Control measures include placebos, active medicine, no-treatment, dosage forms and regimens, historical comparisons, etc. When randomization using mathematical techniques, such as the use of a random numbers table, is employed to assign patients to test or control treatments, the trial is characterized as a RANDOMIZED CONTROLLED TRIAL.

Annotation

this heading is used as a Publication Type; for original report of the conduct or results of a specific controlled clinical trial; a different heading CONTROLLED CLINICAL TRIALS AS TOPIC is used for general design, methodology, economics, etc. of clinical trials

DUI

D018848 MeSH Browser

CUI

M0028202

History note

2008(1995)