A beta-lactam antibiotic produced by the actinobacterium Streptomyces clavuligerus. It is a suicide inhibitor of bacterial beta-lactamase enzymes. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with other beta-lactam antibiotics it prevents antibiotic inactivation by microbial lactamase.

DUI

D019818 MeSH Prohlížeč

CUI

M0029416

CAS

4-Oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, (2R-(2alpha,3Z,5alpha))

Předchozí užití

Clavulanic Acids (1978-1997); Lactams (1976-1982)

Historická pozn.

98; use CLAVULANIC ACID (NM) 1980-97

Veřejná pozn.

98; CLAVULANIC ACID was indexed under CLAVULANIC ACIDS 1978-97 & LACTAMS 1976-82