Clavulanic Acid [kyselina klavulanová]
topical
10
- Terms
-
klavulanát
-
BRL-14151
Clavulanate
Clavulanate Potassium
Clavulanic Acid, Monopotassium Salt
Clavulanic Acid, Monosodium Salt
MM-14151
Potassium Clavulanate
Sodium Clavulanate
Persistent link
https://www.medvik.cz/link/D019818
Definition
A beta-lactam antibiotic produced by the actinobacterium Streptomyces clavuligerus. It is a suicide inhibitor of bacterial beta-lactamase enzymes. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with other beta-lactam antibiotics it prevents antibiotic inactivation by microbial lactamase.
- DUI
- D019818 MeSH Browser
- CUI
- M0029416
- CAS
- 4-Oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, (2R-(2alpha,3Z,5alpha))
- Previous indexing
- Clavulanic Acids (1978-1997); Lactams (1976-1982)
- History note
- 98; use CLAVULANIC ACID (NM) 1980-97
- Public note
- 98; CLAVULANIC ACID was indexed under CLAVULANIC ACIDS 1978-97 & LACTAMS 1976-82
Combination
- analogs & derivatives
- Clavulanic Acids
Allowable subheadings
- AD
- administration & dosage 4
- AE
- adverse effects 1
- AG
- agonists 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 0
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- EC
- economics 0
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 0
- PK
- pharmacokinetics 2
- PD
- pharmacology 1
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 5
- TO
- toxicity 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs