geny p16 [Genes, p16]

tematický
19
Termíny

gen CDKN2
gen CDKN2A
gen MTS1
gen p16INK4A
geny CDKN2
geny CDKN2A
geny MTS1
geny p16INK4
geny p16INK4A

 

CDKN2 Genes
Genes, CDKN2
Genes, CDKN2A
Genes, MTS1
Genes, p16INK4
Genes, p16INK4A
MTS1 Genes
p16 Genes
p16INK4 Genes

Perzistentní odkaz   https://www.medvik.cz/link/D019942
Definice

Tumor supresorové geny uložené na lidském chromozomu 9 (lokus 9p21). Mutace nebo ztráta tohoto genu je spojená s širokým spektrem nádorových onemocnění. Gen p16 kóduje dva produkty (alternativní sestřih): inhibitor p16 cyklin-dependentní kinasy a nádorový supresorový protein p14ARF.

Tumor suppressor genes located on human chromosome 9 in the region 9p21. This gene is either deleted or mutated in a wide range of malignancies. (From Segen, Current Med Talk, 1995) Two alternatively spliced gene products are encoded by p16: CYCLIN-DEPENDENT KINASE INHIBITOR P16 and TUMOR SUPPRESSOR PROTEIN P14ARF.

DUI
D019942 MeSH Prohlížeč
CUI
M0029616
Předchozí užití
Genes, Suppressor, Tumor (1994-1997)
Historická pozn.
98
Veřejná pozn.
98

G Jevy a procesy
G05.360.340 genom 364
G05.360.340.024 komponenty genomu 13
G05.360.340.024.340 geny 674
G05.360.340.024.340.375 geny nádorové 34
G05.360.340.024.340.375.249 tumor supresorové geny 165
G05.360.340.024.340.375.249.050 geny APC 40
G05.360.340.024.340.375.249.100 geny BRCA1 280
G05.360.340.024.340.375.249.105 geny BRCA2 248
G05.360.340.024.340.375.249.200 geny DCC 2
G05.360.340.024.340.375.249.320 geny MCC
G05.360.340.024.340.375.249.340 geny neurofibromatózy 1 14
G05.360.340.024.340.375.249.345 geny neurofibromatózy 2 1
G05.360.340.024.340.375.249.375 geny p16 19
G05.360.340.024.340.375.249.385 geny p53 264
G05.360.340.024.340.375.249.400 geny retinoblastomu 15
G05.360.340.024.340.375.249.420 geny Wilmsova nádoru 20
G05.360.340.024.340.415 geny recesivní 49
G05.360.340.024.340.415.400 tumor supresorové geny 165
G05.360.340.024.340.415.400.050 geny APC 40
G05.360.340.024.340.415.400.100 geny BRCA1 280
G05.360.340.024.340.415.400.105 geny BRCA2 248
G05.360.340.024.340.415.400.200 geny DCC 2
G05.360.340.024.340.415.400.320 geny MCC
G05.360.340.024.340.415.400.340 geny neurofibromatózy 1 14
G05.360.340.024.340.415.400.345 geny neurofibromatózy 2 1
G05.360.340.024.340.415.400.375 geny p16 19
G05.360.340.024.340.415.400.385 geny p53 264
G05.360.340.024.340.415.400.400 geny retinoblastomu 15
G05.360.340.024.340.415.400.420 geny Wilmsova nádoru 20