MAP kinasy kinas (kinas) [MAP Kinase Kinase Kinases]

tematický
48
Termíny

kináza MAP3
kinázy MAP3
kinázy MEK
MAP kinázy kináz (kináz)
MAPK-ERK kinasy kinas
MAPK-ERK kinázy kináz
MAPKKKs
MEK kinasy
MEKKs

 

Kinases, MAP Kinase Kinase
MAP Kinase Kinase Kinase
MAP3 Kinase
MAP3 Kinases
MAPK-ERK Kinase Kinase
MAPK-ERK Kinase Kinases
MAPKKK
MAPKKKs
MEK Kinase
MEK Kinases
MEKK
MEKKs
Mitogen-Activated Protein Kinase Kinase Kinase
Mitogen-Activated Protein Kinase Kinase Kinases

Perzistentní odkaz   https://www.medvik.cz/link/D020930
Definice

Mitogenem aktivované proteinkinázy kinázy kinázy (MAPKKK) jsou serin-threoninové proteinkinázy, které iniciují proteinkinázové signální kaskády. Fosforylují mitogenem aktivované proteinové kinázy kinázy (MAPKK), které zase fosforylují mitogenem aktivované proteinkinázy (MAPK).

Mitogen-activated protein kinase kinase kinases (MAPKKKs) are serine-threonine protein kinases that initiate protein kinase signaling cascades. They phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES; (MAPKKs) which in turn phosphorylate MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs).

DUI
D020930 MeSH Prohlížeč
CUI
M0328033
Předchozí užití
Protein Kinases (1989-1999); Protein-Serine-Threonine Kinases (1993-1999); Protein-Tyrosine Kinase (1989-1999)
Historická pozn.
2000; use MAP KINASE KINASE KINASE 1992-1999
Veřejná pozn.
2000; MAP KINASE KINASE KINASE (now MAP KINASE KINASE KINASES) was indexed under PROTEIN-SERINE-THREONINE KINASES 1992-1999

Povolená podhesla

AN
analýza 1
AI
antagonisté a inhibitory 37
AD
aplikace a dávkování 1
BI
biosyntéza 0
CS
chemická syntéza 0
CH
chemie 0
HI
dějiny 0
EC
ekonomika 0
PK
farmakokinetika 0
PD
farmakologie 2
PH
fyziologie 0
GE
genetika 4
IM
imunologie 0
IP
izolace a purifikace 1
CL
klasifikace 0
BL
krev 0
ME
metabolismus 6
UR
moč 0
CF
mozkomíšní mok 0
DF
nedostatek 0
ST
normy 0
PO
otrava 0
AE
škodlivé účinky 1
TU
terapeutické užití 13
TO
toxicita 1
DE
účinky léků 2
RE
účinky záření 0
UL
ultrastruktura 0
SD
zásobování a distribuce 0

D Chemikálie a léčiva
D08 enzymy a koenzymy 7
D08.811 enzymy 1 547
D08.811.913 transferasy 72
D08.811.913.696 fosfotransferasy 69
D08.811.913.696.620 fosfotransferasy s alkoholovou skupinou jako akceptorem 32
D08.811.913.696.620.682 proteinkinasy 248
D08.811.913.696.620.682.700 protein-serin-threoninkinasy 271
D08.811.913.696.620.682.700.062 aktivinové receptory 5
D08.811.913.696.620.682.700.074 kinasy AMP aktivovaných proteinkinas 1
D08.811.913.696.620.682.700.085 proteinkinasy aktivované AMP 41
D08.811.913.696.620.682.700.097 ATM protein 89
D08.811.913.696.620.682.700.103 kinasy Aurora 4
D08.811.913.696.620.682.700.108 homolog Atg1
D08.811.913.696.620.682.700.109 receptory kostního morfogenetického proteinu 3
D08.811.913.696.620.682.700.125 proteinkinasy závislé na vápníku a kalmodulinu 10
D08.811.913.696.620.682.700.140 kaseinkinasy 1
D08.811.913.696.620.682.700.143 checkpoint kinasa 1 19
D08.811.913.696.620.682.700.145 checkpoint kinasa 2 49
D08.811.913.696.620.682.700.150 cyklickými nukleotidy regulované proteinkinasy
D08.811.913.696.620.682.700.250 proteinkinasa aktivovaná DNA 14
D08.811.913.696.620.682.700.275 kinasy podobné doublecortinu
D08.811.913.696.620.682.700.288 kinasy Dyrk
D08.811.913.696.620.682.700.300 kinasa eIF-2 8
D08.811.913.696.620.682.700.364 kinasy receptorů spřažených s G-proteiny 2
D08.811.913.696.620.682.700.397 kinázy zárodečného centra 2
D08.811.913.696.620.682.700.429 kinasy glykogensynthasy
D08.811.913.696.620.682.700.494 kinasa I-kappa B 9
D08.811.913.696.620.682.700.526 kinázy asociované s receptory interleukinu-1 3
D08.811.913.696.620.682.700.534 LRRK2 2
D08.811.913.696.620.682.700.542 Lim-kinasy 2
D08.811.913.696.620.682.700.559 MAP kinasy kinas (kinas) 48
D08.811.913.696.620.682.700.559.100 MAP kinasa-kinasa-kinasa 1 2
D08.811.913.696.620.682.700.559.200 MAP kinasa-kinasa-kinasa 2 1
D08.811.913.696.620.682.700.559.300 MAP kinasa-kinasa-kinasa 3 1
D08.811.913.696.620.682.700.559.400 MAP kinasa-kinasa-kinasa 4
D08.811.913.696.620.682.700.559.500 MAP kinasa-kinasa-kinasa 5 5
D08.811.913.696.620.682.700.559.650 MAP kinasa-kinasa-kinasa 11
D08.811.913.696.620.682.700.559.800 protoonkogenní proteiny c-mos 2
D08.811.913.696.620.682.700.559.842 raf kinasy 70
D08.811.913.696.620.682.700.565 mitogenem aktivované proteinkinasy kinas 40
D08.811.913.696.620.682.700.567 mitogenem aktivované proteinkinasy 100
D08.811.913.696.620.682.700.576 DM-kinasa 2
D08.811.913.696.620.682.700.579 kinasa indukující NF-kappaB 1
D08.811.913.696.620.682.700.581 kinasy NEK 4
D08.811.913.696.620.682.700.586 onkogenní protein v-akt 5
D08.811.913.696.620.682.700.596 p21 aktivované kinasy 9
D08.811.913.696.620.682.700.606 fytochrom A 2
D08.811.913.696.620.682.700.616 polo-like kinasy
D08.811.913.696.620.682.700.626 pozitivní transkripční elongační faktor b 4
D08.811.913.696.620.682.700.646 proteinkinasy řízené prolinem 1
D08.811.913.696.620.682.700.725 proteinkinasa C 138
D08.811.913.696.620.682.700.745 proteinkinasy PDK
D08.811.913.696.620.682.700.750 proteinkinasa D2
D08.811.913.696.620.682.700.755 protoonkogenní proteiny c-akt 116
D08.811.913.696.620.682.700.759 protoonkogenní proteiny c-bcr 19
D08.811.913.696.620.682.700.776 protoonkogenní proteiny c-pim-1 1
D08.811.913.696.620.682.700.783 PDH-kinasa
D08.811.913.696.620.682.700.789 TGF-beta receptor I. typu 2
D08.811.913.696.620.682.700.795 TGF-beta receptor II. typu
D08.811.913.696.620.682.700.801 serin-threoninkinasy interagující s receptory 7
D08.811.913.696.620.682.700.814 kinázy asociované s Rho 26
D08.811.913.696.620.682.700.862 kinasy ribozomálního proteinu S6 1
D08.811.913.696.620.682.700.897 serin-threoninkinasa 3
D08.811.913.696.620.682.700.931 TOR serin-threoninkinasy 193
D08.811.913.696.620.682.700.965 vakuolární třídící protein VPS15
D08.811.913.696.620.682.700.982 lysin-deficitní proteinkinasa WNK
D12 aminokyseliny, peptidy a proteiny 16
D12.776 proteiny 2 575
D12.776.476 intracelulární signální peptidy a proteiny 174
D12.776.476.563 protein-serin-threoninkinasy 271
D12.776.476.563.062 aktivinové receptory 5
D12.776.476.563.074 kinasy AMP aktivovaných proteinkinas 1
D12.776.476.563.085 proteinkinasy aktivované AMP 41
D12.776.476.563.097 ATM protein 89
D12.776.476.563.103 kinasy Aurora 4
D12.776.476.563.108 homolog Atg1
D12.776.476.563.109 receptory kostního morfogenetického proteinu 3
D12.776.476.563.125 proteinkinasy závislé na vápníku a kalmodulinu 10
D12.776.476.563.140 kaseinkinasy 1
D12.776.476.563.143 checkpoint kinasa 1 19
D12.776.476.563.145 checkpoint kinasa 2 49
D12.776.476.563.150 cyklickými nukleotidy regulované proteinkinasy
D12.776.476.563.250 proteinkinasa aktivovaná DNA 14
D12.776.476.563.275 kinasy podobné doublecortinu
D12.776.476.563.288 kinasy Dyrk
D12.776.476.563.300 kinasa eIF-2 8
D12.776.476.563.364 kinasy receptorů spřažených s G-proteiny 2
D12.776.476.563.397 kinázy zárodečného centra 2
D12.776.476.563.429 kinasy glykogensynthasy
D12.776.476.563.494 kinasa I-kappa B 9
D12.776.476.563.526 kinázy asociované s receptory interleukinu-1 3
D12.776.476.563.534 LRRK2 2
D12.776.476.563.542 Lim-kinasy 2
D12.776.476.563.554 MAP kinasy kinas (kinas) 48
D12.776.476.563.554.100 MAP kinasa-kinasa-kinasa 1 2
D12.776.476.563.554.200 MAP kinasa-kinasa-kinasa 2 1
D12.776.476.563.554.300 MAP kinasa-kinasa-kinasa 3 1
D12.776.476.563.554.400 MAP kinasa-kinasa-kinasa 4
D12.776.476.563.554.500 MAP kinasa-kinasa-kinasa 5 5
D12.776.476.563.554.650 MAP kinasa-kinasa-kinasa 11
D12.776.476.563.554.800 protoonkogenní proteiny c-mos 2
D12.776.476.563.554.842 raf kinasy 70
D12.776.476.563.565 mitogenem aktivované proteinkinasy kinas 40
D12.776.476.563.567 mitogenem aktivované proteinkinasy 100
D12.776.476.563.576 DM-kinasa 2
D12.776.476.563.579 kinasa indukující NF-kappaB 1
D12.776.476.563.581 kinasy NEK 4
D12.776.476.563.586 onkogenní protein v-akt 5
D12.776.476.563.596 p21 aktivované kinasy 9
D12.776.476.563.606 fytochrom A 2
D12.776.476.563.616 polo-like kinasy
D12.776.476.563.626 pozitivní transkripční elongační faktor b 4
D12.776.476.563.646 proteinkinasy řízené prolinem 1
D12.776.476.563.725 proteinkinasa C 138
D12.776.476.563.745 proteinkinasy PDK
D12.776.476.563.750 proteinkinasa D2
D12.776.476.563.755 protoonkogenní proteiny c-akt 116
D12.776.476.563.759 protoonkogenní proteiny c-bcr 19
D12.776.476.563.776 protoonkogenní proteiny c-pim-1 1
D12.776.476.563.783 PDH-kinasa
D12.776.476.563.789 TGF-beta receptor I. typu 2
D12.776.476.563.795 TGF-beta receptor II. typu
D12.776.476.563.801 serin-threoninkinasy interagující s receptory 7
D12.776.476.563.814 kinázy asociované s Rho 26
D12.776.476.563.862 kinasy ribozomálního proteinu S6 1
D12.776.476.563.897 serin-threoninkinasa 3
D12.776.476.563.931 TOR serin-threoninkinasy 193
D12.776.476.563.965 vakuolární třídící protein VPS15
D12.776.476.563.982 lysin-deficitní proteinkinasa WNK

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