MAP Kinase Kinase Kinases [MAP kinasy kinas (kinas)]

topical
48
Terms

kináza MAP3
kinázy MAP3
kinázy MEK
MAP kinázy kináz (kináz)
MAPK-ERK kinasy kinas
MAPK-ERK kinázy kináz
MAPKKKs
MEK kinasy
MEKKs

 

Kinases, MAP Kinase Kinase
MAP Kinase Kinase Kinase
MAP3 Kinase
MAP3 Kinases
MAPK-ERK Kinase Kinase
MAPK-ERK Kinase Kinases
MAPKKK
MAPKKKs
MEK Kinase
MEK Kinases
MEKK
MEKKs
Mitogen-Activated Protein Kinase Kinase Kinase
Mitogen-Activated Protein Kinase Kinase Kinases

Persistent link   https://www.medvik.cz/link/D020930
Definition

Mitogen-activated protein kinase kinase kinases (MAPKKKs) are serine-threonine protein kinases that initiate protein kinase signaling cascades. They phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES; (MAPKKs) which in turn phosphorylate MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs).

DUI
D020930 MeSH Browser
CUI
M0328033
Previous indexing
Protein Kinases (1989-1999); Protein-Serine-Threonine Kinases (1993-1999); Protein-Tyrosine Kinase (1989-1999)
History note
2000; use MAP KINASE KINASE KINASE 1992-1999
Public note
2000; MAP KINASE KINASE KINASE (now MAP KINASE KINASE KINASES) was indexed under PROTEIN-SERINE-THREONINE KINASES 1992-1999

Allowable subheadings

AD
administration & dosage 1
AE
adverse effects 1
AN
analysis 1
AI
antagonists & inhibitors 37
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects 2
EC
economics
GE
genetics 4
HI
history
IM
immunology
IP
isolation & purification 1
ME
metabolism 6
PK
pharmacokinetics
PD
pharmacology 2
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use 13
TO
toxicity 1
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 547
D08.811.913 Transferases 72
D08.811.913.696 Phosphotransferases 69
D08.811.913.696.620 Phosphotransferases (Alcohol Group Acceptor) 32
D08.811.913.696.620.682 Protein Kinases 248
D08.811.913.696.620.682.700 Protein Serine-Threonine Kinases 271
D08.811.913.696.620.682.700.062 Activin Receptors 5
D08.811.913.696.620.682.700.074 AMP-Activated Protein Kinase Kinases 1
D08.811.913.696.620.682.700.085 AMP-Activated Protein Kinases 41
D08.811.913.696.620.682.700.097 Ataxia Telangiectasia Mutated Proteins 89
D08.811.913.696.620.682.700.103 Aurora Kinases 4
D08.811.913.696.620.682.700.108 Autophagy-Related Protein-1 Homolog
D08.811.913.696.620.682.700.109 Bone Morphogenetic Protein Receptors 3
D08.811.913.696.620.682.700.125 Calcium-Calmodulin-Dependent Protein Kinases 10
D08.811.913.696.620.682.700.140 Casein Kinases 1
D08.811.913.696.620.682.700.143 Checkpoint Kinase 1 19
D08.811.913.696.620.682.700.145 Checkpoint Kinase 2 49
D08.811.913.696.620.682.700.150 Cyclic Nucleotide-Regulated Protein Kinases
D08.811.913.696.620.682.700.250 DNA-Activated Protein Kinase 14
D08.811.913.696.620.682.700.275 Doublecortin-Like Kinases
D08.811.913.696.620.682.700.288 Dyrk Kinases
D08.811.913.696.620.682.700.300 eIF-2 Kinase 8
D08.811.913.696.620.682.700.364 G-Protein-Coupled Receptor Kinases 2
D08.811.913.696.620.682.700.397 Germinal Center Kinases 2
D08.811.913.696.620.682.700.429 Glycogen Synthase Kinases
D08.811.913.696.620.682.700.494 I-kappa B Kinase 9
D08.811.913.696.620.682.700.526 Interleukin-1 Receptor-Associated Kinases 3
D08.811.913.696.620.682.700.534 Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 2
D08.811.913.696.620.682.700.542 Lim Kinases 2
D08.811.913.696.620.682.700.559 MAP Kinase Kinase Kinases 48
D08.811.913.696.620.682.700.559.100 MAP Kinase Kinase Kinase 1 2
D08.811.913.696.620.682.700.559.200 MAP Kinase Kinase Kinase 2 1
D08.811.913.696.620.682.700.559.300 MAP Kinase Kinase Kinase 3 1
D08.811.913.696.620.682.700.559.400 MAP Kinase Kinase Kinase 4
D08.811.913.696.620.682.700.559.500 MAP Kinase Kinase Kinase 5 5
D08.811.913.696.620.682.700.559.650 Mitogen-Activated Protein Kinase Kinase Kinase 11
D08.811.913.696.620.682.700.559.800 Proto-Oncogene Proteins c-mos 2
D08.811.913.696.620.682.700.559.842 raf Kinases 70
D08.811.913.696.620.682.700.565 Mitogen-Activated Protein Kinase Kinases 41
D08.811.913.696.620.682.700.567 Mitogen-Activated Protein Kinases 100
D08.811.913.696.620.682.700.576 Myotonin-Protein Kinase 2
D08.811.913.696.620.682.700.579 NF-kappaB-Inducing Kinase 1
D08.811.913.696.620.682.700.581 NIMA-Related Kinases 4
D08.811.913.696.620.682.700.586 Oncogene Protein v-akt 5
D08.811.913.696.620.682.700.596 p21-Activated Kinases 9
D08.811.913.696.620.682.700.606 Phytochrome A 2
D08.811.913.696.620.682.700.616 Polo-like Kinases
D08.811.913.696.620.682.700.626 Positive Transcriptional Elongation Factor B 4
D08.811.913.696.620.682.700.646 Proline-Directed Protein Kinases 1
D08.811.913.696.620.682.700.725 Protein Kinase C 138
D08.811.913.696.620.682.700.745 3-Phosphoinositide-Dependent Protein Kinases
D08.811.913.696.620.682.700.750 Protein Kinase D2
D08.811.913.696.620.682.700.755 Proto-Oncogene Proteins c-akt 117
D08.811.913.696.620.682.700.759 Proto-Oncogene Proteins c-bcr 19
D08.811.913.696.620.682.700.776 Proto-Oncogene Proteins c-pim-1 1
D08.811.913.696.620.682.700.783 Pyruvate Dehydrogenase Acetyl-Transferring Kinase
D08.811.913.696.620.682.700.789 Receptor, Transforming Growth Factor-beta Type I 2
D08.811.913.696.620.682.700.795 Receptor, Transforming Growth Factor-beta Type II
D08.811.913.696.620.682.700.801 Receptor-Interacting Protein Serine-Threonine Kinases 7
D08.811.913.696.620.682.700.814 rho-Associated Kinases 26
D08.811.913.696.620.682.700.862 Ribosomal Protein S6 Kinases 1
D08.811.913.696.620.682.700.897 Serine-Threonine Kinase 3
D08.811.913.696.620.682.700.931 TOR Serine-Threonine Kinases 193
D08.811.913.696.620.682.700.965 Vacuolar Sorting Protein VPS15
D08.811.913.696.620.682.700.982 WNK Lysine-Deficient Protein Kinase 1
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 577
D12.776.476 Intracellular Signaling Peptides and Proteins 174
D12.776.476.563 Protein Serine-Threonine Kinases 271
D12.776.476.563.062 Activin Receptors 5
D12.776.476.563.074 AMP-Activated Protein Kinase Kinases 1
D12.776.476.563.085 AMP-Activated Protein Kinases 41
D12.776.476.563.097 Ataxia Telangiectasia Mutated Proteins 89
D12.776.476.563.103 Aurora Kinases 4
D12.776.476.563.108 Autophagy-Related Protein-1 Homolog
D12.776.476.563.109 Bone Morphogenetic Protein Receptors 3
D12.776.476.563.125 Calcium-Calmodulin-Dependent Protein Kinases 10
D12.776.476.563.140 Casein Kinases 1
D12.776.476.563.143 Checkpoint Kinase 1 19
D12.776.476.563.145 Checkpoint Kinase 2 49
D12.776.476.563.150 Cyclic Nucleotide-Regulated Protein Kinases
D12.776.476.563.250 DNA-Activated Protein Kinase 14
D12.776.476.563.275 Doublecortin-Like Kinases
D12.776.476.563.288 Dyrk Kinases
D12.776.476.563.300 eIF-2 Kinase 8
D12.776.476.563.364 G-Protein-Coupled Receptor Kinases 2
D12.776.476.563.397 Germinal Center Kinases 2
D12.776.476.563.429 Glycogen Synthase Kinases
D12.776.476.563.494 I-kappa B Kinase 9
D12.776.476.563.526 Interleukin-1 Receptor-Associated Kinases 3
D12.776.476.563.534 Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 2
D12.776.476.563.542 Lim Kinases 2
D12.776.476.563.554 MAP Kinase Kinase Kinases 48
D12.776.476.563.554.100 MAP Kinase Kinase Kinase 1 2
D12.776.476.563.554.200 MAP Kinase Kinase Kinase 2 1
D12.776.476.563.554.300 MAP Kinase Kinase Kinase 3 1
D12.776.476.563.554.400 MAP Kinase Kinase Kinase 4
D12.776.476.563.554.500 MAP Kinase Kinase Kinase 5 5
D12.776.476.563.554.650 Mitogen-Activated Protein Kinase Kinase Kinase 11
D12.776.476.563.554.800 Proto-Oncogene Proteins c-mos 2
D12.776.476.563.554.842 raf Kinases 70
D12.776.476.563.565 Mitogen-Activated Protein Kinase Kinases 41
D12.776.476.563.567 Mitogen-Activated Protein Kinases 100
D12.776.476.563.576 Myotonin-Protein Kinase 2
D12.776.476.563.579 NF-kappaB-Inducing Kinase 1
D12.776.476.563.581 NIMA-Related Kinases 4
D12.776.476.563.586 Oncogene Protein v-akt 5
D12.776.476.563.596 p21-Activated Kinases 9
D12.776.476.563.606 Phytochrome A 2
D12.776.476.563.616 Polo-like Kinases
D12.776.476.563.626 Positive Transcriptional Elongation Factor B 4
D12.776.476.563.646 Proline-Directed Protein Kinases 1
D12.776.476.563.725 Protein Kinase C 138
D12.776.476.563.745 3-Phosphoinositide-Dependent Protein Kinases
D12.776.476.563.750 Protein Kinase D2
D12.776.476.563.755 Proto-Oncogene Proteins c-akt 117
D12.776.476.563.759 Proto-Oncogene Proteins c-bcr 19
D12.776.476.563.776 Proto-Oncogene Proteins c-pim-1 1
D12.776.476.563.783 Pyruvate Dehydrogenase Acetyl-Transferring Kinase
D12.776.476.563.789 Receptor, Transforming Growth Factor-beta Type I 2
D12.776.476.563.795 Receptor, Transforming Growth Factor-beta Type II
D12.776.476.563.801 Receptor-Interacting Protein Serine-Threonine Kinases 7
D12.776.476.563.814 rho-Associated Kinases 26
D12.776.476.563.862 Ribosomal Protein S6 Kinases 1
D12.776.476.563.897 Serine-Threonine Kinase 3
D12.776.476.563.931 TOR Serine-Threonine Kinases 193
D12.776.476.563.965 Vacuolar Sorting Protein VPS15
D12.776.476.563.982 WNK Lysine-Deficient Protein Kinase 1

ANP1 kinase Chemical MeSH Browser

ANP2 protein, Arabidopsis Chemical MeSH Browser

ANP3 protein, Arabidopsis Chemical MeSH Browser

ASK1 protein, Drosophila Chemical MeSH Browser

At1g73660 protein, Arabidopsis Chemical MeSH Browser

BCK1 protein, Pneumocystis carinii Chemical MeSH Browser

BYR2 protein, S pombe Chemical MeSH Browser

DLK-1 protein, C elegans Chemical MeSH Browser

Lzk protein, mouse Chemical MeSH Browser

MAP kinase kinase kinase 6 Chemical MeSH Browser

MAP kinase kinase kinase 7 Chemical MeSH Browser

MAP kinase kinase kinase ubc4 Chemical MeSH Browser

MAP3K10 protein, human Chemical MeSH Browser

MAP3K13 protein, human Chemical MeSH Browser

MAP3K15 protein, human Chemical MeSH Browser

MAP3K19 protein, human Chemical MeSH Browser

MAP3K20 protein, human Chemical MeSH Browser

MAP3K21 protein, human Chemical MeSH Browser

MAP3K8 protein, human Chemical MeSH Browser

MAP3K9 protein, human Chemical MeSH Browser

MAP3Kepsilon2 protein, Arabidopsis Chemical MeSH Browser

MAPKKK18 protein, Arabidopsis Chemical MeSH Browser

MEKK1 protein, Arabidopsis Chemical MeSH Browser

MLK-like mitogen-activated protein triple kinase Chemical MeSH Browser

Map3k10 protein, mouse Chemical MeSH Browser

Map3k15 protein, mouse Chemical MeSH Browser

Map3k8 protein, mouse Chemical MeSH Browser

Map3k8 protein, rat Chemical MeSH Browser

Map3k9 protein, mouse Chemical MeSH Browser

Map3k9 protein, rat Chemical MeSH Browser

Mkh1 protein, S pombe Chemical MeSH Browser

NPK1 protein, Nicotiana tabacum Chemical MeSH Browser

REKS protein, Xenopus Chemical MeSH Browser

Raf10 protein, Arabidopsis Chemical MeSH Browser

Raf11 protein, Arabidopsis Chemical MeSH Browser

Raf43 protein, Arabidopsis Chemical MeSH Browser

Ras-dependent mitogen-activated protein kinase kinase kinase Chemical MeSH Browser

SSK2 protein, S cerevisiae Chemical MeSH Browser

SSK22 protein, S cerevisiae Chemical MeSH Browser

STE20 protein, S cerevisiae Chemical MeSH Browser

Ste11 protein, S cerevisiae Chemical MeSH Browser

TAK1 protein, Drosophila Chemical MeSH Browser

YODA protein, Arabidopsis Chemical MeSH Browser

ZAK protein, mouse Chemical MeSH Browser

insulin-stimulated MEK kinase Chemical MeSH Browser

map3k10 protein, Xenopus Chemical MeSH Browser

mitogen-activated protein kinase kinase kinase 12 Chemical MeSH Browser

slpr protein, Drosophila Chemical MeSH Browser

wis4 protein, S pombe Chemical MeSH Browser

wnd protein, Drosophila Chemical MeSH Browser

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