Multifunkční protein, který obsahuje Fe-S komplex. Je zároveň regulačním proteinem železa a cytoplazmatickou formou akonitáthydratázy. Váže se na regulační prvky železa nacházející se na mRNA a zapojené do metabolismu železa a reguluje jejich translaci. Jeho schopnost vázat RNA a jeho akonitátová hydrolázová aktivita závisí na dostupnosti železa.

A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form of aconitate hydratase. It binds to iron regulatory elements found on mRNAs involved in iron metabolism and regulates their translation. Its RNA binding ability and its aconitate hydrolase activity are dependent upon availability of IRON.

DUI

D035941 MeSH Prohlížeč

CUI

M0175229

Předchozí užití

Ribonucleoproteins (1995-2002); Iron-Sulfur Proteins (1995-2002)

Historická pozn.

2003; for FERRITIN REPRESSOR PROTEIN use IRON-REGULATORY PROTEINS (NM) 1991-2002, for IRE-BP1, IRON REGULATORY PROTEIN 1, IRP-1 PROTEIN & IRP1 PROTEIN use IRON-REGULATORY PROTEINS (NM) 1995-2002

Veřejná pozn.

2003; FERRITIN REPRESSOR PROTEIN was indexed under IRON-SULFUR PROTEINS & RNA-BINDING PROTEINS 1991-2002, IRE-BP1, IRON REGULATORY PROTEIN 1, IRP-1 PROTEIN & IRP1 PROTEIN were indexed under IRON-SULFUR PROTEINS & RNA-BINDING PROTEINS 1995-2002