Silent Information Regulator Proteins, Saccharomyces cerevisiae [proteiny regulace mlčící informace, Saccharomyces cerevisiae]
- Terms
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proteiny SIR, S cerevisiae
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Silent Information Regulator Proteins, S cerevisiae
Silent Mating Type Information Regulator Protein, S cerevisiae
SIR Proteins, S cerevisiae
A set of nuclear proteins in SACCHAROMYCES CEREVISIAE that are required for the transcriptional repression of the silent mating type loci. They mediate the formation of silenced CHROMATIN and repress both transcription and recombination at other loci as well. They are comprised of 4 non-homologous, interacting proteins, Sir1p, Sir2p, Sir3p, and Sir4p. Sir2p, an NAD-dependent HISTONE DEACETYLASE, is the founding member of the family of SIRTUINS.
- DUI
- D038281 MeSH Browser
- CUI
- M0415710
- History note
- 2003
- Public note
- 2003
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
SIR1 protein, S cerevisiae Chemical MeSH Browser
SIR2 protein, S cerevisiae Chemical MeSH Browser
SIR3 protein, S cerevisiae Chemical MeSH Browser
SIR4 protein, S cerevisiae Chemical MeSH Browser