Mad2 Proteins [Mad2 protein]

topical
1
Terms

protein Mad2

 

Mad2 Mitotic Arrest Deficient-like 1 Proteins

Persistent link   https://www.medvik.cz/link/D064246
Definition

Mad2 is a component of the spindle-assembly checkpoint apparatus. It binds to and inhibits the Cdc20 activator subunit of the anaphase-promoting complex, preventing the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Mad2 is required for proper microtubule capture at KINETOCHORES.

DUI
D064246 MeSH Browser
CUI
M0580530
History note
2014
Public note
2014; was indexed under CELL CYCLE PROTEINS 2000-2013 and NUCLEAR PROTEINS 2005-2013

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics 1
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 581
D12.776.167 Cell Cycle Proteins 330
D12.776.167.024 Anaphase-Promoting Complex-Cyclosome 12
D12.776.167.049 Aurora Kinases 4
D12.776.167.100 cdc25 Phosphatases 28
D12.776.167.150 Cellular Apoptosis Susceptibility Protein 4
D12.776.167.163 Cohesins
D12.776.167.175 Cullin Proteins 7
D12.776.167.187 Cyclin-Dependent Kinase Inhibitor Proteins 44
D12.776.167.200 Cyclin-Dependent Kinases 231
D12.776.167.218 Cyclins 112
D12.776.167.242 F-Box-WD Repeat-Containing Protein 7 3
D12.776.167.254 GADD45 Proteins
D12.776.167.265 Geminin 1
D12.776.167.313 Mad2 Proteins 1
D12.776.167.409 Minichromosome Maintenance Proteins 4
D12.776.167.457 NIMA-Related Kinases 4
D12.776.167.469 Polo-like Kinases
D12.776.167.481 S100 Calcium Binding Protein A6 2
D12.776.167.504 Securin 1
D12.776.167.552 Separase 1
D12.776.167.564 Structural Maintenance of Chromosome Protein 1
D12.776.167.576 Survivin 6
D12.776.167.600 Tumor Suppressor Protein p14ARF 4
D12.776.167.800 Valosin Containing Protein 3
D12.776.660 Nuclear Proteins 455
D12.776.660.049 Antennapedia Homeodomain Protein 1
D12.776.660.075 Ataxins 2
D12.776.660.100 BRCA1 Protein 103
D12.776.660.105 BRCA2 Protein 97
D12.776.660.167 CCAAT-Enhancer-Binding Proteins 11
D12.776.660.201 CDX2 Transcription Factor 3
D12.776.660.235 Chromosomal Proteins, Non-Histone 93
D12.776.660.264 Fanconi Anemia Complementation Group A Protein 1
D12.776.660.285 Fanconi Anemia Complementation Group D2 Protein 4
D12.776.660.289 Fanconi Anemia Complementation Group E Protein
D12.776.660.293 Fanconi Anemia Complementation Group F Protein
D12.776.660.323 Fanconi Anemia Complementation Group N Protein 4
D12.776.660.338 GADD45 Proteins
D12.776.660.352 Hepatocyte Nuclear Factors 5
D12.776.660.415 Homeobox Protein Nkx-2.2
D12.776.660.478 Host Cell Factor C1 2
D12.776.660.486 Immunoglobulin J Recombination Signal Sequence-Binding Protein
D12.776.660.494 Inhibitor of Growth Protein 1
D12.776.660.502 Karyopherins 9
D12.776.660.526 Mad2 Proteins 1
D12.776.660.551 Mediator Complex 5
D12.776.660.600 NF-kappa B 220
D12.776.660.625 Antigens, Nuclear 11
D12.776.660.650 Nuclear Matrix-Associated Proteins 2
D12.776.660.675 Nuclear Receptor Coactivators 6
D12.776.660.688 Nuclear Receptor Interacting Protein 1 3
D12.776.660.691 Nucleolin
D12.776.660.694 Nucleophosmin 19
D12.776.660.700 Oncogene Protein p55(v-myc) 1
D12.776.660.720 Poly-ADP-Ribose Binding Proteins 5
D12.776.660.740 Proliferating Cell Nuclear Antigen 60
D12.776.660.745 Promyelocytic Leukemia Protein 4
D12.776.660.750 Protamines 43
D12.776.660.760 Proto-Oncogene Proteins c-fos 62
D12.776.660.763 Proto-Oncogene Proteins c-jun 18
D12.776.660.764 Proto-Oncogene Proteins c-mdm2 65
D12.776.660.765 Proto-Oncogene Proteins c-myc 67
D12.776.660.767 Proto-Oncogene Proteins c-rel 2
D12.776.660.768 ran GTP-Binding Protein 4
D12.776.660.769 Retinoblastoma Binding Proteins 3
D12.776.660.770 Retinoblastoma-Like Protein p107 4
D12.776.660.794 Retinoblastoma-Like Protein p130 5
D12.776.660.807 Retinoblastoma Protein 52
D12.776.660.820 Silent Information Regulator Proteins, Saccharomyces cerevisiae
D12.776.660.823 Thyroid Nuclear Factor 1
D12.776.660.912 Tumor Protein p73 6

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