Survivin [survivin]
- Terms
-
BIRC5
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Baculoviral IAP Repeat-containing Protein 5
BIRC5 Protein
An apoptosis inhibitory protein that contains a single baculoviral IAP repeat (BIR) domain. It associates with MICROTUBULES and functions to regulate cell proliferation as a component of the chromosome passage protein complex (CPC), performing essential roles for localization of the complex, chromosome alignment, segregation during MITOSIS and CYTOKINESIS, and assembly of the MITOTIC SPINDLE. It is expressed by fetal kidney and liver cells and highly expressed in ADENOCARCINOMA and high-grade LYMPHOMA.
- DUI
- D000077022 MeSH Browser
- CUI
- M000639155
- Previous indexing
- Inhibitor of Apoptosis Proteins (2012-2018); Microtubule-Associated Proteins (1997-2018); Neoplasm Proteins (1997-2018)
- History note
- 2019
- Public note
- 2019
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 1
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 3
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
BIRC5 protein, human Chemical MeSH Browser
Bir1 protein, S pombe Chemical MeSH Browser
Birc5 protein, mouse Chemical MeSH Browser
Birc5 protein, rat Chemical MeSH Browser
Birc5a protein, zebrafish Chemical MeSH Browser
Det protein, Drosophila Chemical MeSH Browser
HIV-TAT-survivin (T34A) protein Chemical MeSH Browser
birc5.2 protein, Xenopus Chemical MeSH Browser
survivin protein, Xenopus laevis Chemical MeSH Browser