An apoptosis inhibitory protein that contains a single baculoviral IAP repeat (BIR) domain. It associates with MICROTUBULES and functions to regulate cell proliferation as a component of the chromosome passage protein complex (CPC), performing essential roles for localization of the complex, chromosome alignment, segregation during MITOSIS and CYTOKINESIS, and assembly of the MITOTIC SPINDLE. It is expressed by fetal kidney and liver cells and highly expressed in ADENOCARCINOMA and high-grade LYMPHOMA.

DUI

D000077022 MeSH Prohlížeč

CUI

M000639155

Předchozí užití

Inhibitor of Apoptosis Proteins (2012-2018); Microtubule-Associated Proteins (1997-2018); Neoplasm Proteins (1997-2018)

Historická pozn.

2019

Veřejná pozn.

2019