Neuropilin-1 [neuropilin-1]
- Terms
-
A5 Antigen
Npn-1 Protein
NRP1 Protein
Sema III Receptor
Semaphorin III Receptor
A dimeric cell surface receptor involved in angiogenesis (NEOVASCULARIZATION, PHYSIOLOGICAL) and AXONAL GUIDANCE. Neuropilin-1 is a 140-kDa transmembrane protein that binds CLASS 3 SEMAPHORINS, and several other growth factors. Neuropilin-1 forms complexes with plexins or VEGF RECEPTORS; their binding affinity and specificity are determined by the composition of the neuropilin dimer and the identity of other receptors complexed with it. Neuropilin-1 is expressed in distinct patterns during neural development, complementary to those described for NEUROPILIN-2.
- DUI
- D039942 MeSH Browser
- CUI
- M0191842
- Previous indexing
- Nerve Tissue Proteins (1991-2002)
- History note
- 2003; use NEUROPILIN-1 (NM) 1991-2002
- Public note
- 2003; A5 ANTIGEN (now NEUROPILIN-1) was indexed under NERVE TISSUE PROTEINS 1991-2002
Allowable subheadings
- AD
- administration & dosage
- AG
- agonists
- AN
- analysis 1
- AI
- antagonists & inhibitors 1
- BI
- biosynthesis 1
- BL
- blood 1
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- GE
- genetics 2
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 2
- PH
- physiology 1
- RE
- radiation effects
- TU
- therapeutic use
- UL
- ultrastructure
NRP1 protein, human Chemical MeSH Browser