Transmembrane receptor for CLASS 3 SEMAPHORINS and several vascular endothelial growth factor isoforms. Neuropilin-2 functions either as a homodimer or as a heterodimer with NEUROPILIN-1. The binding affinity of neuropilin-2 varies for different class 3 semaphorin isoforms and is dependent on the composition of the dimer. The protein also forms receptor complexes with plexins and with VEGF RECEPTORS, which alters the binding characteristics of the receptor.

DUI

D039943 MeSH Browser

CUI

M0377884

Previous indexing

Nerve Tissue Proteins (1998-2002)

History note

2003; for NPN-2 PROTEIN use NEUROPILIN-1 1998-2002

Public note

2003; NPN-2 PROTEIN was indexed under NERVE TISSUE PROTEINS 1998-2002