Ketol-Acid Reductoisomerase [reduktoizomeráza pro obousměrnou transformaci ketokyselin]

topical
1
Terms

izomeroreduktáza
reduktoisomerasa pro ketol-kyseliny
reduktoisomerasa pro obousměrnou transformaci ketokyselin na hydroxykyseliny

 

Acetohydroxy Acid Isomeroreductase
Alpha-Acetohydroxyacid Isomeroreductase
Dihydroxyisovalerate Dehydrogenase (Isomerizing)
Hydroxyacid Reductoisomerase
Isomeroreductase

Persistent link   https://www.medvik.cz/link/D050540
Definition

An enzyme that catalyzes the oxidation of (R)-2,3-dihydroxy-3-methylbutanoate to (S)-2-hydroxy-2-methyl-3-oxobutanoate in the presence of NADP. It is involved in the biosynthesis of VALINE; LEUCINE; ISOLEUCINE; pentothenate and COENZYME A. This enzyme was formerly classified as EC 1.1.1.89.

DUI
D050540 MeSH Browser
CUI
M0076427
History note
2006(1980); use VALERATES 1970-1979
Public note
2006; KETOL-ACID REDUCTOISOMERASE was indexed under ALCOHOL OXODOREDUCTASES 1983-2000, & under VALERATES 1970-1982

Allowable subheadings

AD
administration & dosage 0
AE
adverse effects 0
AN
analysis 0
AI
antagonists & inhibitors 0
BI
biosynthesis 0
BL
blood 0
CF
cerebrospinal fluid 0
CS
chemical synthesis 0
CH
chemistry 0
CL
classification 0
DF
deficiency 0
DE
drug effects 0
EC
economics 0
GE
genetics 1
HI
history 0
IM
immunology 0
IP
isolation & purification 0
ME
metabolism 1
PK
pharmacokinetics 0
PD
pharmacology 0
PH
physiology 0
PO
poisoning 0
RE
radiation effects 0
ST
standards 0
SD
supply & distribution 0
TU
therapeutic use 0
TO
toxicity 0
UL
ultrastructure 0
UR
urine 0

D Chemicals and Drugs
D01 Inorganic Chemicals 68
D02 Organic Chemicals 391
D03 Heterocyclic Compounds 189
D04 Polycyclic Compounds 65
D05 Macromolecular Substances 103
D06 Hormones, Hormone Substitutes, and Hormone Antagonists 43
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 547
D08.811.682 Oxidoreductases 446
D08.811.682.047 Alcohol Oxidoreductases 97
D08.811.682.047.820 NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases
D08.811.682.047.820.100 11-beta-Hydroxysteroid Dehydrogenases 16
D08.811.682.047.820.125 20-Hydroxysteroid Dehydrogenases 7
D08.811.682.047.820.150 3-Hydroxyacyl CoA Dehydrogenases 15
D08.811.682.047.820.186 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) 2
D08.811.682.047.820.193 3-Isopropylmalate Dehydrogenase
D08.811.682.047.820.196 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase
D08.811.682.047.820.200 Acetoin Dehydrogenase
D08.811.682.047.820.250 Alcohol Dehydrogenase 55
D08.811.682.047.820.284 Aldo-Keto Reductases 3
D08.811.682.047.820.289 Carbonyl Reductase (NADPH) 2
D08.811.682.047.820.293 Glycerol-3-Phosphate Dehydrogenase (NAD+) 1
D08.811.682.047.820.300 Homoserine Dehydrogenase 1
D08.811.682.047.820.350 Hydroxybutyrate Dehydrogenase 5
D08.811.682.047.820.375 Hydroxyprostaglandin Dehydrogenases 10
D08.811.682.047.820.400 Hydroxypyruvate Reductase
D08.811.682.047.820.450 IMP Dehydrogenase 2
D08.811.682.047.820.475 Isocitrate Dehydrogenase 55
D08.811.682.047.820.487 Ketol-Acid Reductoisomerase 1
D08.811.682.047.820.493 L-Lactate Dehydrogenase 242
D08.811.682.047.820.496 Malate Dehydrogenase 88
D08.811.682.047.820.498 Malate Dehydrogenase (NADP+) 1
D08.811.682.047.820.500 Progesterone Reductase 2
D08.811.682.047.820.800 D-Xylulose Reductase
D08.811.682.047.820.900 Short Chain Dehydrogenase-Reductases 2
D09 Carbohydrates 723
D10 Lipids 2 524
D12 Amino Acids, Peptides, and Proteins 16
D13 Nucleic Acids, Nucleotides, and Nucleosides 9
D20 Complex Mixtures 19
D23 Biological Factors 143
D25 Biomedical and Dental Materials 110
D26 Pharmaceutical Preparations 7 031
D27 Chemical Actions and Uses 374

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