Campomelic Dysplasia [kampomelická dysplazie]

topical
1
Terms

akampomelická kampomelická dysplazie
kamptomelická dysplazie

 

Acampomelic Campomelic Dysplasia
Campomelic Dwarfism
Campomelic Syndrome
Camptomelic Dysplasia
Cmpd1 Sra1

Persistent link   https://www.medvik.cz/link/D055036
Definition

A congenital disorder of CHONDROGENESIS and OSTEOGENESIS characterized by hypoplasia of endochondral bones. In most cases there is a curvature of the long bones especially the TIBIA with dimpling of the skin over the bowed areas, malformation of the pelvis and spine, 11 pairs of ribs, hypoplastic scapulae, club feet, micrognathia, CLEFT PALATE, tracheobronchomalacia, and in some patients male-to-female sex reversal (SEX REVERSAL, GONADAL). Most patients die in the neonatal period of respiratory distress. Campomelic dysplasia is associated with haploinsufficiency of the SOX9 TRANSCRIPTION FACTOR gene.

DUI
D055036 MeSH Browser
CUI
M0513026
History note
2009
Public note
2009

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