TOR Serine-Threonine Kinases [TOR serin-threoninkinasy]
- Terms
-
kinasy TOR
kinázy TOR
protein mTOR
protein RAFT-1
TOR kinázy
TOR serin-threoninkinázy
TOR serin-treoninkinázy
-
FK506 Binding Protein 12-Rapamycin Associated Protein 1
FKBP12-Rapamycin Associated Protein
FKBP12-Rapamycin Complex-Associated Protein
Mammalian Target of Rapamycin
Mechanistic Target of Rapamycin Protein
mTOR Protein
mTOR Serine-Threonine Kinase
mTOR Serine-Threonine Kinases
RAFT-1 Protein
Rapamycin Target Protein
Target of Rapamycin Protein
Target of Rapamycin Proteins
TOR Kinase
TOR Kinases
TOR Serine-Threonine Kinase
A serine threonine kinase that controls a wide range of growth-related cellular processes. The protein is referred to as the target of RAPAMYCIN due to the discovery that SIROLIMUS (commonly known as rapamycin) forms an inhibitory complex with TACROLIMUS BINDING PROTEIN 1A that blocks the action of its enzymatic activity.
- DUI
- D058570 MeSH Browser
- CUI
- M0543256
- History note
- 2011
- Public note
- 2011; MTOR PROTEIN (now TOR SERINE-THREONINE KINASES) was indexed under PROTEIN KINASES 1995-2010 and under PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR) 1995-2001
Allowable subheadings
- AD
- administration & dosage 18
- AE
- adverse effects 12
- AN
- analysis 1
- AI
- antagonists & inhibitors 111
- BI
- biosynthesis 2
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 9
- EC
- economics 1
- GE
- genetics 12
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 40
- PK
- pharmacokinetics 17
- PD
- pharmacology 6
- PH
- physiology 4
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 49
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0